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A HIF-regulated VHL-PTP1B-Src signaling axis identifies a therapeutic target in renal cell carcinoma.
Suwaki N, Vanhecke E, Atkins KM, Graf M, Swabey K, Huang P, Schraml P, Moch H, Cassidy AM, Brewer D, Al-Lazikani B, Workman P, De-Bono J, Kaye SB, Larkin J, Gore ME, Sawyers CL, Nelson P, Beer TM, Geng H, Gao L, Qian DZ, Alumkal JJ, Thomas G, Thomas GV. Suwaki N, et al. Sci Transl Med. 2011 Jun 1;3(85):85ra47. doi: 10.1126/scitranslmed.3002004. Sci Transl Med. 2011. PMID: 21632985 Free PMC article.
Objective assessment of cancer genes for drug discovery.
Patel MN, Halling-Brown MD, Tym JE, Workman P, Al-Lazikani B. Patel MN, et al. Nat Rev Drug Discov. 2013 Jan;12(1):35-50. doi: 10.1038/nrd3913. Nat Rev Drug Discov. 2013. PMID: 23274470 Review.
Drugging cancer genomes.
Workman P, Al-Lazikani B. Workman P, et al. Nat Rev Drug Discov. 2013 Dec;12(12):889-90. doi: 10.1038/nrd4184. Nat Rev Drug Discov. 2013. PMID: 24287764 No abstract available.
canSAR: an updated cancer research and drug discovery knowledgebase.
Tym JE, Mitsopoulos C, Coker EA, Razaz P, Schierz AC, Antolin AA, Al-Lazikani B. Tym JE, et al. Nucleic Acids Res. 2016 Jan 4;44(D1):D938-43. doi: 10.1093/nar/gkv1030. Epub 2015 Dec 15. Nucleic Acids Res. 2016. PMID: 26673713 Free PMC article.
74 results