Parrott N - Search Results

1

Prediction of pH-Dependent Drug-Drug Interactions for Basic Drugs Using Physiologically Based Biopharmaceutics Modeling: Industry Case Studies.

Mitra A, Parrott N, Miller N, Lloyd R, Tistaert C, Heimbach T, Ji Y, Kesisoglou F. Mitra A, et al. Among authors: parrott n. J Pharm Sci. 2020 Mar;109(3):1380-1394. doi: 10.1016/j.xphs.2019.11.017. Epub 2019 Nov 25. J Pharm Sci. 2020. PMID: 31778721

2

Prediction of intestinal absorption: comparative assessment of GASTROPLUS and IDEA.

Parrott N, Lavé T. Parrott N, et al. Eur J Pharm Sci. 2002 Oct;17(1-2):51-61. doi: 10.1016/s0928-0987(02)00132-x. Eur J Pharm Sci. 2002. PMID: 12356420

3

An evaluation of the utility of physiologically based models of pharmacokinetics in early drug discovery.

Parrott N, Paquereau N, Coassolo P, Lavé T. Parrott N, et al. J Pharm Sci. 2005 Oct;94(10):2327-43. doi: 10.1002/jps.20419. J Pharm Sci. 2005. PMID: 16136543

4

A strategy for preclinical formulation development using GastroPlus as pharmacokinetic simulation tool and a statistical screening design applied to a dog study.

Kuentz M, Nick S, Parrott N, Röthlisberger D. Kuentz M, et al. Among authors: parrott n. Eur J Pharm Sci. 2006 Jan;27(1):91-9. doi: 10.1016/j.ejps.2005.08.011. Epub 2005 Oct 10. Eur J Pharm Sci. 2006. PMID: 16219449

5

A novel strategy for physiologically based predictions of human pharmacokinetics.

Jones HM, Parrott N, Jorga K, Lavé T. Jones HM, et al. Among authors: parrott n. Clin Pharmacokinet. 2006;45(5):511-42. doi: 10.2165/00003088-200645050-00006. Clin Pharmacokinet. 2006. PMID: 16640456

6

Predicting pharmacokinetic food effects using biorelevant solubility media and physiologically based modelling.

Jones HM, Parrott N, Ohlenbusch G, Lavé T. Jones HM, et al. Among authors: parrott n. Clin Pharmacokinet. 2006;45(12):1213-26. doi: 10.2165/00003088-200645120-00006. Clin Pharmacokinet. 2006. PMID: 17112297

7

Applications of physiologically based absorption models in drug discovery and development.

Parrott N, Lave T. Parrott N, et al. Mol Pharm. 2008 Sep-Oct;5(5):760-75. doi: 10.1021/mp8000155. Epub 2008 Jun 12. Mol Pharm. 2008. PMID: 18547054

8

Predicting pharmacokinetics of drugs using physiologically based modeling--application to food effects.

Parrott N, Lukacova V, Fraczkiewicz G, Bolger MB. Parrott N, et al. AAPS J. 2009 Mar;11(1):45-53. doi: 10.1208/s12248-008-9079-7. Epub 2009 Jan 29. AAPS J. 2009. PMID: 19184451 Free PMC article. Review.

9

Use of physiologically based pharmacokinetic modeling for assessment of drug-drug interactions.

Baneyx G, Fukushima Y, Parrott N. Baneyx G, et al. Among authors: parrott n. Future Med Chem. 2012 Apr;4(5):681-93. doi: 10.4155/fmc.12.13. Future Med Chem. 2012. PMID: 22458685 Review.

10

Application of PBPK modeling to predict human intestinal metabolism of CYP3A substrates - an evaluation and case study using GastroPlus.

Heikkinen AT, Baneyx G, Caruso A, Parrott N. Heikkinen AT, et al. Among authors: parrott n. Eur J Pharm Sci. 2012 Sep 29;47(2):375-86. doi: 10.1016/j.ejps.2012.06.013. Epub 2012 Jul 1. Eur J Pharm Sci. 2012. PMID: 22759901

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