Godfrey JD - Search Results

1

eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5'UTR.

Wilczynska A, Gillen SL, Schmidt T, Meijer HA, Jukes-Jones R, Langlais C, Kopra K, Lu WT, Godfrey JD, Hawley BR, Hodge K, Zanivan S, Cain K, Le Quesne J, Bushell M. Wilczynska A, et al. Among authors: godfrey jd. Genome Biol. 2019 Dec 2;20(1):262. doi: 10.1186/s13059-019-1857-2. Genome Biol. 2019. PMID: 31791371 Free PMC article.

2

Translational repression and eIF4A2 activity are critical for microRNA-mediated gene regulation.

Meijer HA, Kong YW, Lu WT, Wilczynska A, Spriggs RV, Robinson SW, Godfrey JD, Willis AE, Bushell M. Meijer HA, et al. Among authors: godfrey jd. Science. 2013 Apr 5;340(6128):82-5. doi: 10.1126/science.1231197. Science. 2013. PMID: 23559250

3

MiR-142-3p is downregulated in aggressive p53 mutant mouse models of pancreatic ductal adenocarcinoma by hypermethylation of its locus.

Godfrey JD, Morton JP, Wilczynska A, Sansom OJ, Bushell MD. Godfrey JD, et al. Cell Death Dis. 2018 May 29;9(6):644. doi: 10.1038/s41419-018-0628-4. Cell Death Dis. 2018. PMID: 29844410 Free PMC article.

4

A novel role for GSK3β as a modulator of Drosha microprocessor activity and MicroRNA biogenesis.

Fletcher CE, Godfrey JD, Shibakawa A, Bushell M, Bevan CL. Fletcher CE, et al. Among authors: godfrey jd. Nucleic Acids Res. 2017 Mar 17;45(5):2809-2828. doi: 10.1093/nar/gkw938. Nucleic Acids Res. 2017. PMID: 27907888 Free PMC article.

5

The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration.

Hall AE, Lu WT, Godfrey JD, Antonov AV, Paicu C, Moxon S, Dalmay T, Wilczynska A, Muller PA, Bushell M. Hall AE, et al. Among authors: godfrey jd. Cell Death Dis. 2016 Apr 7;7(4):e2184. doi: 10.1038/cddis.2016.91. Cell Death Dis. 2016. PMID: 27054339 Free PMC article.

6

Control of backbone chemistry and chirality boost oligonucleotide splice switching activity.

Kandasamy P, McClorey G, Shimizu M, Kothari N, Alam R, Iwamoto N, Kumarasamy J, Bommineni GR, Bezigian A, Chivatakarn O, Butler DCD, Byrne M, Chwalenia K, Davies KE, Desai J, Shelke JD, Durbin AF, Ellerington R, Edwards B, Godfrey J, Hoss A, Liu F, Longo K, Lu G, Marappan S, Oieni J, Paik IH, Estabrook EP, Shivalila C, Tischbein M, Kawamoto T, Rinaldi C, Rajão-Saraiva J, Tripathi S, Yang H, Yin Y, Zhao X, Zhou C, Zhang J, Apponi L, Wood MJA, Vargeese C. Kandasamy P, et al. Among authors: godfrey j. Nucleic Acids Res. 2022 Jun 10;50(10):5443-5466. doi: 10.1093/nar/gkac018. Nucleic Acids Res. 2022. PMID: 35061895 Free PMC article.

7

Endogenous ADAR-mediated RNA editing in non-human primates using stereopure chemically modified oligonucleotides.

Monian P, Shivalila C, Lu G, Shimizu M, Boulay D, Bussow K, Byrne M, Bezigian A, Chatterjee A, Chew D, Desai J, Favaloro F, Godfrey J, Hoss A, Iwamoto N, Kawamoto T, Kumarasamy J, Lamattina A, Lindsey A, Liu F, Looby R, Marappan S, Metterville J, Murphy R, Rossi J, Pu T, Bhattarai B, Standley S, Tripathi S, Yang H, Yin Y, Yu H, Zhou C, Apponi LH, Kandasamy P, Vargeese C. Monian P, et al. Nat Biotechnol. 2022 Jul;40(7):1093-1102. doi: 10.1038/s41587-022-01225-1. Epub 2022 Mar 7. Nat Biotechnol. 2022. PMID: 35256816

8

Quantitative Measurement of Cytosolic and Nuclear Penetration of Oligonucleotide Therapeutics.

Deprey K, Batistatou N, Debets MF, Godfrey J, VanderWall KB, Miles RR, Shehaj L, Guo J, Andreucci A, Kandasamy P, Lu G, Shimizu M, Vargeese C, Kritzer JA. Deprey K, et al. ACS Chem Biol. 2022 Feb 18;17(2):348-360. doi: 10.1021/acschembio.1c00830. Epub 2022 Jan 15. ACS Chem Biol. 2022. PMID: 35034446 Free PMC article.

9

α1ACT Is Essential for Survival and Early Cerebellar Programming in a Critical Neonatal Window.

Du X, Wei C, Hejazi Pastor DP, Rao ER, Li Y, Grasselli G, Godfrey J, Palmenberg AC, Andrade J, Hansel C, Gomez CM. Du X, et al. Neuron. 2019 May 22;102(4):770-785.e7. doi: 10.1016/j.neuron.2019.02.036. Epub 2019 Mar 25. Neuron. 2019. PMID: 30922876 Free PMC article.

10

HER2 c-Terminal Fragments Are Expressed via Internal Translation of the HER2 mRNA.

Godfrey JD, Hejazi D, Du X, Wei C, Rao E, Gomez CM. Godfrey JD, et al. Int J Mol Sci. 2022 Aug 23;23(17):9549. doi: 10.3390/ijms23179549. Int J Mol Sci. 2022. PMID: 36076950 Free PMC article.

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