Le Quesne J - Search Results

1

eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5'UTR.

Wilczynska A, Gillen SL, Schmidt T, Meijer HA, Jukes-Jones R, Langlais C, Kopra K, Lu WT, Godfrey JD, Hawley BR, Hodge K, Zanivan S, Cain K, Le Quesne J, Bushell M. Wilczynska A, et al. Among authors: le quesne j. Genome Biol. 2019 Dec 2;20(1):262. doi: 10.1186/s13059-019-1857-2. Genome Biol. 2019. PMID: 31791371 Free PMC article.

2

Spatial Positioning of Immune Hotspots Reflects the Interplay between B and T Cells in Lung Squamous Cell Carcinoma.

Zhang H, AbdulJabbar K, Moore DA, Akarca A, Enfield KSS, Jamal-Hanjani M, Raza SEA, Veeriah S, Salgado R, McGranahan N, Le Quesne J, Swanton C, Marafioti T, Yuan Y. Zhang H, et al. Among authors: le quesne j. Cancer Res. 2023 May 2;83(9):1410-1425. doi: 10.1158/0008-5472.CAN-22-2589. Cancer Res. 2023. PMID: 36853169 Free PMC article.

3

Identification of a motif that mediates polypyrimidine tract-binding protein-dependent internal ribosome entry.

Mitchell SA, Spriggs KA, Bushell M, Evans JR, Stoneley M, Le Quesne JP, Spriggs RV, Willis AE. Mitchell SA, et al. Genes Dev. 2005 Jul 1;19(13):1556-71. doi: 10.1101/gad.339105. Genes Dev. 2005. PMID: 15998809 Free PMC article.

4

Dysregulation of protein synthesis and disease.

Le Quesne JP, Spriggs KA, Bushell M, Willis AE. Le Quesne JP, et al. J Pathol. 2010 Jan;220(2):140-51. doi: 10.1002/path.2627. J Pathol. 2010. PMID: 19827082 Review.

5

Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf).

Chernova T, Murphy FA, Galavotti S, Sun XM, Powley IR, Grosso S, Schinwald A, Zacarias-Cabeza J, Dudek KM, Dinsdale D, Le Quesne J, Bennett J, Nakas A, Greaves P, Poland CA, Donaldson K, Bushell M, Willis AE, MacFarlane M. Chernova T, et al. Among authors: le quesne j. Curr Biol. 2017 Nov 6;27(21):3302-3314.e6. doi: 10.1016/j.cub.2017.09.007. Curr Biol. 2017. PMID: 29112861 Free PMC article.

6

mRNA structural elements immediately upstream of the start codon dictate dependence upon eIF4A helicase activity.

Waldron JA, Tack DC, Ritchey LE, Gillen SL, Wilczynska A, Turro E, Bevilacqua PC, Assmann SM, Bushell M, Le Quesne J. Waldron JA, et al. Among authors: le quesne j. Genome Biol. 2019 Dec 30;20(1):300. doi: 10.1186/s13059-019-1901-2. Genome Biol. 2019. PMID: 31888698 Free PMC article.

7

Nanomolar Protein-Protein Interaction Monitoring with a Label-Free Protein-Probe Technique.

Valtonen S, Vuorinen E, Kariniemi T, Eskonen V, Le Quesne J, Bushell M, Härmä H, Kopra K. Valtonen S, et al. Among authors: le quesne j. Anal Chem. 2020 Dec 15;92(24):15781-15788. doi: 10.1021/acs.analchem.0c02823. Epub 2020 Nov 25. Anal Chem. 2020. PMID: 33237744 Free PMC article.

8

Mutant p53 promotes RCP-dependent chemoresistance coinciding with increased delivery of P-glycoprotein to the plasma membrane.

Phatak V, von Grabowiecki Y, Janus J, Officer L, Behan C, Aschauer L, Pinon L, Mackay H, Zanivan S, Norman JC, Kelly M, Le Quesne J, Muller PAJ. Phatak V, et al. Among authors: le quesne j. Cell Death Dis. 2021 Feb 24;12(2):207. doi: 10.1038/s41419-021-03497-y. Cell Death Dis. 2021. PMID: 33627632 Free PMC article.

9

The pathogenesis of mesothelioma is driven by a dysregulated translatome.

Grosso S, Marini A, Gyuraszova K, Voorde JV, Sfakianos A, Garland GD, Tenor AR, Mordue R, Chernova T, Morone N, Sereno M, Smith CP, Officer L, Farahmand P, Rooney C, Sumpton D, Das M, Teodósio A, Ficken C, Martin MG, Spriggs RV, Sun XM, Bushell M, Sansom OJ, Murphy D, MacFarlane M, Le Quesne JPC, Willis AE. Grosso S, et al. Among authors: le quesne jpc. Nat Commun. 2021 Aug 13;12(1):4920. doi: 10.1038/s41467-021-25173-7. Nat Commun. 2021. PMID: 34389715 Free PMC article.

10

A mutation in the c-myc-IRES leads to enhanced internal ribosome entry in multiple myeloma: a novel mechanism of oncogene de-regulation.

Chappell SA, LeQuesne JP, Paulin FE, deSchoolmeester ML, Stoneley M, Soutar RL, Ralston SH, Helfrich MH, Willis AE. Chappell SA, et al. Oncogene. 2000 Sep 7;19(38):4437-40. doi: 10.1038/sj.onc.1203791. Oncogene. 2000. PMID: 10980620

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