Lagares D - Search Results

1

Evasion of apoptosis by myofibroblasts: a hallmark of fibrotic diseases.

Hinz B, Lagares D. Hinz B, et al. Among authors: lagares d. Nat Rev Rheumatol. 2020 Jan;16(1):11-31. doi: 10.1038/s41584-019-0324-5. Epub 2019 Dec 2. Nat Rev Rheumatol. 2020. PMID: 31792399 Free PMC article. Review.

2

Targeting focal adhesion kinase in fibrotic diseases.

Lagares D, Kapoor M. Lagares D, et al. BioDrugs. 2013 Feb;27(1):15-23. doi: 10.1007/s40259-012-0003-4. BioDrugs. 2013. PMID: 23329396 Review.

3

Fibrosis--a lethal component of systemic sclerosis.

Ho YY, Lagares D, Tager AM, Kapoor M. Ho YY, et al. Among authors: lagares d. Nat Rev Rheumatol. 2014 Jul;10(7):390-402. doi: 10.1038/nrrheum.2014.53. Epub 2014 Apr 22. Nat Rev Rheumatol. 2014. PMID: 24752182 Review.

4

ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis.

Lagares D, Ghassemi-Kakroodi P, Tremblay C, Santos A, Probst CK, Franklin A, Santos DM, Grasberger P, Ahluwalia N, Montesi SB, Shea BS, Black KE, Knipe R, Blati M, Baron M, Wu B, Fahmi H, Gandhi R, Pardo A, Selman M, Wu J, Pelletier JP, Martel-Pelletier J, Tager AM, Kapoor M. Lagares D, et al. Nat Med. 2017 Dec;23(12):1405-1415. doi: 10.1038/nm.4419. Epub 2017 Oct 23. Nat Med. 2017. PMID: 29058717 Free PMC article.

5

Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis.

Lagares D, Santos A, Grasberger PE, Liu F, Probst CK, Rahimi RA, Sakai N, Kuehl T, Ryan J, Bhola P, Montero J, Kapoor M, Baron M, Varelas X, Tschumperlin DJ, Letai A, Tager AM. Lagares D, et al. Sci Transl Med. 2017 Dec 13;9(420):eaal3765. doi: 10.1126/scitranslmed.aal3765. Sci Transl Med. 2017. PMID: 29237758 Free PMC article.

6

Matrix Stiffness: the Conductor of Organ Fibrosis.

Santos A, Lagares D. Santos A, et al. Among authors: lagares d. Curr Rheumatol Rep. 2018 Jan 19;20(1):2. doi: 10.1007/s11926-018-0710-z. Curr Rheumatol Rep. 2018. PMID: 29349703 Review.

7

BH3 mimetics as anti-fibrotic therapy: Unleashing the mitochondrial pathway of apoptosis in myofibroblasts.

Kuehl T, Lagares D. Kuehl T, et al. Among authors: lagares d. Matrix Biol. 2018 Aug;68-69:94-105. doi: 10.1016/j.matbio.2018.01.020. Epub 2018 Jan 31. Matrix Biol. 2018. PMID: 29408011 Review.

8

Ephrins and Eph Receptor Signaling in Tissue Repair and Fibrosis.

Wu B, Rockel JS, Lagares D, Kapoor M. Wu B, et al. Among authors: lagares d. Curr Rheumatol Rep. 2019 Apr 12;21(6):23. doi: 10.1007/s11926-019-0825-x. Curr Rheumatol Rep. 2019. PMID: 30980212 Free PMC article. Review.

9

Senotherapeutics: Targeting senescence in idiopathic pulmonary fibrosis.

Merkt W, Bueno M, Mora AL, Lagares D. Merkt W, et al. Among authors: lagares d. Semin Cell Dev Biol. 2020 May;101:104-110. doi: 10.1016/j.semcdb.2019.12.008. Epub 2019 Dec 24. Semin Cell Dev Biol. 2020. PMID: 31879264 Free PMC article. Review.

10

Mechano-therapeutics: Targeting Mechanical Signaling in Fibrosis and Tumor Stroma.

Tschumperlin DJ, Lagares D. Tschumperlin DJ, et al. Among authors: lagares d. Pharmacol Ther. 2020 Aug;212:107575. doi: 10.1016/j.pharmthera.2020.107575. Epub 2020 May 11. Pharmacol Ther. 2020. PMID: 32437826 Free PMC article. Review.

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