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Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages.
Abuhammad A, Fullam E, Lowe ED, Staunton D, Kawamura A, Westwood IM, Bhakta S, Garner AC, Wilson DL, Seden PT, Davies SG, Russell AJ, Garman EF, Sim E. Abuhammad A, et al. Among authors: lowe ed. PLoS One. 2012;7(12):e52790. doi: 10.1371/journal.pone.0052790. Epub 2012 Dec 28. PLoS One. 2012. PMID: 23285185 Free PMC article.
Structure of arylamine N-acetyltransferase from Mycobacterium tuberculosis determined by cross-seeding with the homologous protein from M. marinum: triumph over adversity.
Abuhammad A, Lowe ED, McDonough MA, Shaw Stewart PD, Kolek SA, Sim E, Garman EF. Abuhammad A, et al. Among authors: lowe ed. Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1433-46. doi: 10.1107/S0907444913015126. Epub 2013 Jul 17. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 23897467
Heterotypic interactions drive antibody synergy against a malaria vaccine candidate.
Ragotte RJ, Pulido D, Lias AM, Quinkert D, Alanine DGW, Jamwal A, Davies H, Nacer A, Lowe ED, Grime GW, Illingworth JJ, Donat RF, Garman EF, Bowyer PW, Higgins MK, Draper SJ. Ragotte RJ, et al. Among authors: lowe ed. Nat Commun. 2022 Feb 17;13(1):933. doi: 10.1038/s41467-022-28601-4. Nat Commun. 2022. PMID: 35177602 Free PMC article.
74 results