van den Bedem H - Search Results

1

Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis.

Dasgupta M, Budday D, de Oliveira SHP, Madzelan P, Marchany-Rivera D, Seravalli J, Hayes B, Sierra RG, Boutet S, Hunter MS, Alonso-Mori R, Batyuk A, Wierman J, Lyubimov A, Brewster AS, Sauter NK, Applegate GA, Tiwari VK, Berkowitz DB, Thompson MC, Cohen AE, Fraser JS, Wall ME, van den Bedem H, Wilson MA. Dasgupta M, et al. Among authors: van den bedem h. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25634-25640. doi: 10.1073/pnas.1901864116. Epub 2019 Dec 4. Proc Natl Acad Sci U S A. 2019. PMID: 31801874 Free PMC article.

2

Microbes 'sieve' ions on their surface to start the nitrogen cycle.

van den Bedem H. van den Bedem H. Nature. 2024 Jun;630(8015):43-44. doi: 10.1038/d41586-024-01351-7. Nature. 2024. PMID: 38811777 No abstract available.

3

Accessing protein conformational ensembles using room-temperature X-ray crystallography.

Fraser JS, van den Bedem H, Samelson AJ, Lang PT, Holton JM, Echols N, Alber T. Fraser JS, et al. Among authors: van den bedem h. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16247-52. doi: 10.1073/pnas.1111325108. Epub 2011 Sep 14. Proc Natl Acad Sci U S A. 2011. PMID: 21918110 Free PMC article.

4

Automated identification of functional dynamic contact networks from X-ray crystallography.

van den Bedem H, Bhabha G, Yang K, Wright PE, Fraser JS. van den Bedem H, et al. Nat Methods. 2013 Sep;10(9):896-902. doi: 10.1038/nmeth.2592. Epub 2013 Aug 4. Nat Methods. 2013. PMID: 23913260 Free PMC article.

5

Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR.

Fenwick RB, van den Bedem H, Fraser JS, Wright PE. Fenwick RB, et al. Among authors: van den bedem h. Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):E445-54. doi: 10.1073/pnas.1323440111. Epub 2014 Jan 13. Proc Natl Acad Sci U S A. 2014. PMID: 24474795 Free PMC article.

6

Crystal cryocooling distorts conformational heterogeneity in a model Michaelis complex of DHFR.

Keedy DA, van den Bedem H, Sivak DA, Petsko GA, Ringe D, Wilson MA, Fraser JS. Keedy DA, et al. Among authors: van den bedem h. Structure. 2014 Jun 10;22(6):899-910. doi: 10.1016/j.str.2014.04.016. Epub 2014 May 29. Structure. 2014. PMID: 24882744 Free PMC article.

7

Integrative, dynamic structural biology at atomic resolution--it's about time.

van den Bedem H, Fraser JS. van den Bedem H, et al. Nat Methods. 2015 Apr;12(4):307-18. doi: 10.1038/nmeth.3324. Nat Methods. 2015. PMID: 25825836 Free PMC article. Review.

8

Geometric analysis characterizes molecular rigidity in generic and non-generic protein configurations.

Budday D, Leyendecker S, van den Bedem H. Budday D, et al. Among authors: van den bedem h. J Mech Phys Solids. 2015 Oct 1;83:36-47. doi: 10.1016/j.jmps.2015.06.006. J Mech Phys Solids. 2015. PMID: 26213417 Free PMC article.

9

Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.

Keedy DA, Kenner LR, Warkentin M, Woldeyes RA, Hopkins JB, Thompson MC, Brewster AS, Van Benschoten AH, Baxter EL, Uervirojnangkoorn M, McPhillips SE, Song J, Alonso-Mori R, Holton JM, Weis WI, Brunger AT, Soltis SM, Lemke H, Gonzalez A, Sauter NK, Cohen AE, van den Bedem H, Thorne RE, Fraser JS. Keedy DA, et al. Among authors: van benschoten ah, van den bedem h. Elife. 2015 Sep 30;4:e07574. doi: 10.7554/eLife.07574. Elife. 2015. PMID: 26422513 Free PMC article.

10

Exposing Hidden Alternative Backbone Conformations in X-ray Crystallography Using qFit.

Keedy DA, Fraser JS, van den Bedem H. Keedy DA, et al. Among authors: van den bedem h. PLoS Comput Biol. 2015 Oct 27;11(10):e1004507. doi: 10.1371/journal.pcbi.1004507. eCollection 2015 Oct. PLoS Comput Biol. 2015. PMID: 26506617 Free PMC article.

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