Galesic A - Search Results

1

Ubiquitination Can Change the Structure of the α-Synuclein Amyloid Fiber in a Site Selective Fashion.

Moon SP, Balana AT, Galesic A, Rakshit A, Pratt MR. Moon SP, et al. Among authors: galesic a. J Org Chem. 2020 Feb 7;85(3):1548-1555. doi: 10.1021/acs.joc.9b02641. Epub 2019 Dec 19. J Org Chem. 2020. PMID: 31809571 Free PMC article.

2

Synthesis of a Bis-thio-acetone (BTA) Analogue of the Lysine Isopeptide Bond and its Application to Investigate the Effects of Ubiquitination and SUMOylation on α-Synuclein Aggregation and Toxicity.

Lewis YE, Abeywardana T, Lin YH, Galesic A, Pratt MR. Lewis YE, et al. Among authors: galesic a. ACS Chem Biol. 2016 Apr 15;11(4):931-42. doi: 10.1021/acschembio.5b01042. Epub 2016 Jan 12. ACS Chem Biol. 2016. PMID: 26726734 Free PMC article.

3

O-GlcNAcylation of α-Synuclein at Serine 87 Reduces Aggregation without Affecting Membrane Binding.

Lewis YE, Galesic A, Levine PM, De Leon CA, Lamiri N, Brennan CK, Pratt MR. Lewis YE, et al. Among authors: galesic a. ACS Chem Biol. 2017 Apr 21;12(4):1020-1027. doi: 10.1021/acschembio.7b00113. Epub 2017 Feb 22. ACS Chem Biol. 2017. PMID: 28195695 Free PMC article.

4

O-GlcNAc modification inhibits the calpain-mediated cleavage of α-synuclein.

Levine PM, De Leon CA, Galesic A, Balana A, Marotta NP, Lewis YE, Pratt MR. Levine PM, et al. Among authors: galesic a. Bioorg Med Chem. 2017 Sep 15;25(18):4977-4982. doi: 10.1016/j.bmc.2017.04.038. Epub 2017 Apr 29. Bioorg Med Chem. 2017. PMID: 28487126 Free PMC article.

5

α-Synuclein O-GlcNAcylation alters aggregation and toxicity, revealing certain residues as potential inhibitors of Parkinson's disease.

Levine PM, Galesic A, Balana AT, Mahul-Mellier AL, Navarro MX, De Leon CA, Lashuel HA, Pratt MR. Levine PM, et al. Among authors: galesic a. Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1511-1519. doi: 10.1073/pnas.1808845116. Epub 2019 Jan 16. Proc Natl Acad Sci U S A. 2019. PMID: 30651314 Free PMC article.

6

Investigating the Effects of O-GlcNAc Modifications in Parkinson's Disease Using Semisynthetic α-Synuclein.

Galesic A, Pratt MR. Galesic A, et al. Methods Mol Biol. 2020;2133:313-326. doi: 10.1007/978-1-0716-0434-2_15. Methods Mol Biol. 2020. PMID: 32144674 Free PMC article.

7

Comparison of N-Acetyl-Glucosamine to Other Monosaccharides Reveals Structural Differences for the Inhibition of α-Synuclein Aggregation.

Galesic A, Rakshit A, Cutolo G, Pacheco RP, Balana AT, Moon SP, Pratt MR. Galesic A, et al. ACS Chem Biol. 2021 Jan 15;16(1):14-19. doi: 10.1021/acschembio.0c00716. Epub 2021 Jan 5. ACS Chem Biol. 2021. PMID: 33399442 Free PMC article.

8

Combining non-canonical amino acid mutagenesis and native chemical ligation for multiply modifying proteins: A case study of α-synuclein post-translational modifications.

Galesic A, Pan B, Ramirez J, Rhoades E, Pratt MR, Petersson EJ. Galesic A, et al. Methods. 2023 Oct;218:101-109. doi: 10.1016/j.ymeth.2023.08.002. Epub 2023 Aug 6. Methods. 2023. PMID: 37549799 Free PMC article.

9

In Vivo Experimental and Analytical Studies for Bevacizumab Diffusion Coefficient Measurement in the Rabbit Vitreous Humor.

Zhang S, Penkova A, Humayun MS, Martinez-Camarillo JC, Tadle AC, Galesic A, Thompson ME, Pratt M, Gonzales-Calle A, Sadhal SS. Zhang S, et al. Among authors: galesic a. J Heat Transfer. 2021 Mar 1;143(3):032101. doi: 10.1115/1.4049033. Epub 2021 Jan 18. J Heat Transfer. 2021. PMID: 33612856 Free PMC article.

10

O-GlcNAc Modification of α-Synuclein Can Alter Monomer Dynamics to Control Aggregation Kinetics.

Gamage K, Wang B, Hard ER, Van T, Galesic A, Phillips GR, Pratt M, Lapidus LJ. Gamage K, et al. Among authors: galesic a. ACS Chem Neurosci. 2024 Aug 21;15(16):3044-3052. doi: 10.1021/acschemneuro.4c00301. Epub 2024 Jul 31. ACS Chem Neurosci. 2024. PMID: 39082221 Free PMC article.

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