Cai L - Search Results

1

Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen.

De Silva D, Zhang Z, Liu Y, Parker JS, Xu C, Cai L, Wang GG, Earp HS, Whang YE. De Silva D, et al. Among authors: cai l. Sci Rep. 2019 Dec 9;9(1):18637. doi: 10.1038/s41598-019-55057-2. Sci Rep. 2019. PMID: 31819114 Free PMC article.

2

NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis.

Wang GG, Cai L, Pasillas MP, Kamps MP. Wang GG, et al. Among authors: cai l. Nat Cell Biol. 2007 Jul;9(7):804-12. doi: 10.1038/ncb1608. Epub 2007 Jun 24. Nat Cell Biol. 2007. PMID: 17589499

3

An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting.

Cai L, Rothbart SB, Lu R, Xu B, Chen WY, Tripathy A, Rockowitz S, Zheng D, Patel DJ, Allis CD, Strahl BD, Song J, Wang GG. Cai L, et al. Mol Cell. 2013 Feb 7;49(3):571-82. doi: 10.1016/j.molcel.2012.11.026. Epub 2012 Dec 27. Mol Cell. 2013. PMID: 23273982 Free PMC article.

4

Androgen receptor signaling regulates DNA repair in prostate cancers.

Polkinghorn WR, Parker JS, Lee MX, Kass EM, Spratt DE, Iaquinta PJ, Arora VK, Yen WF, Cai L, Zheng D, Carver BS, Chen Y, Watson PA, Shah NP, Fujisawa S, Goglia AG, Gopalan A, Hieronymus H, Wongvipat J, Scardino PT, Zelefsky MJ, Jasin M, Chaudhuri J, Powell SN, Sawyers CL. Polkinghorn WR, et al. Among authors: cai l. Cancer Discov. 2013 Nov;3(11):1245-53. doi: 10.1158/2159-8290.CD-13-0172. Epub 2013 Sep 11. Cancer Discov. 2013. PMID: 24027196 Free PMC article.

5

Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia.

Xu B, On DM, Ma A, Parton T, Konze KD, Pattenden SG, Allison DF, Cai L, Rockowitz S, Liu S, Liu Y, Li F, Vedadi M, Frye SV, Garcia BA, Zheng D, Jin J, Wang GG. Xu B, et al. Among authors: cai l. Blood. 2015 Jan 8;125(2):346-57. doi: 10.1182/blood-2014-06-581082. Epub 2014 Nov 13. Blood. 2015. PMID: 25395428 Free PMC article.

6

The Chromatin Remodeler BPTF Activates a Stemness Gene-Expression Program Essential for the Maintenance of Adult Hematopoietic Stem Cells.

Xu B, Cai L, Butler JM, Chen D, Lu X, Allison DF, Lu R, Rafii S, Parker JS, Zheng D, Wang GG. Xu B, et al. Among authors: cai l. Stem Cell Reports. 2018 Mar 13;10(3):675-683. doi: 10.1016/j.stemcr.2018.01.020. Epub 2018 Feb 15. Stem Cell Reports. 2018. PMID: 29456179 Free PMC article.

7

ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer.

Cai L, Tsai YH, Wang P, Wang J, Li D, Fan H, Zhao Y, Bareja R, Lu R, Wilson EM, Sboner A, Whang YE, Zheng D, Parker JS, Earp HS, Wang GG. Cai L, et al. Mol Cell. 2018 Oct 18;72(2):341-354.e6. doi: 10.1016/j.molcel.2018.08.029. Epub 2018 Sep 27. Mol Cell. 2018. PMID: 30270106 Free PMC article.

8

A Model System for Studying the DNMT3A Hotspot Mutation (DNMT3A^R882) Demonstrates a Causal Relationship between Its Dominant-Negative Effect and Leukemogenesis.

Lu R, Wang J, Ren Z, Yin J, Wang Y, Cai L, Wang GG. Lu R, et al. Among authors: cai l. Cancer Res. 2019 Jul 15;79(14):3583-3594. doi: 10.1158/0008-5472.CAN-18-3275. Epub 2019 Jun 4. Cancer Res. 2019. PMID: 31164355 Free PMC article.

9

PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation.

Ren Z, Ahn JH, Liu H, Tsai YH, Bhanu NV, Koss B, Allison DF, Ma A, Storey AJ, Wang P, Mackintosh SG, Edmondson RD, Groen RWJ, Martens AC, Garcia BA, Tackett AJ, Jin J, Cai L, Zheng D, Wang GG. Ren Z, et al. Among authors: cai l. Blood. 2019 Oct 3;134(14):1176-1189. doi: 10.1182/blood.2019000578. Epub 2019 Aug 5. Blood. 2019. PMID: 31383640 Free PMC article.

10

Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion.

Zhang Y, Guo Y, Gough SM, Zhang J, Vann KR, Li K, Cai L, Shi X, Aplan PD, Wang GG, Kutateladze TG. Zhang Y, et al. Among authors: cai l. Nat Commun. 2020 Jul 3;11(1):3339. doi: 10.1038/s41467-020-17098-4. Nat Commun. 2020. PMID: 32620764 Free PMC article.

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