Celastrol Self-Stabilized Nanoparticles for Effective Treatment of Melanoma.
Li J, Jia Y, Zhang P, Yang H, Cong X, An L, Xiao C.
Li J, et al. Among authors: an l.
Int J Nanomedicine. 2020 Feb 19;15:1205-1214. doi: 10.2147/IJN.S232603. eCollection 2020.
Int J Nanomedicine. 2020.
PMID: 32110017
Free PMC article.
METHODS: First, the CEL was chemically conjugated onto a methoxyl poly(ethylene glycol)-b-poly(L-lysine) (mPEG-PLL) backbone, resulting in the conversion of the double hydrophilic mPEG-PLL polymer into an amphiphilic polymer prodrug, mPEG-PLL/CEL. ...Furthermore, th …
METHODS: First, the CEL was chemically conjugated onto a methoxyl poly(ethylene glycol)-b-poly(L-lysine) (mPEG-PLL) backbone, resulti …