Take K - Search Results

1

Inhibition of MGAT2 modulates fat-induced gut peptide release and fat intake in normal mice and ameliorates obesity and diabetes in ob/ob mice fed on a high-fat diet.

Mochida T, Take K, Maki T, Nakakariya M, Adachi R, Sato K, Kitazaki T, Takekawa S. Mochida T, et al. Among authors: take k. FEBS Open Bio. 2020 Mar;10(3):316-326. doi: 10.1002/2211-5463.12778. Epub 2020 Feb 5. FEBS Open Bio. 2020. PMID: 31837122 Free PMC article.

2

Optimization of a novel series of N-phenylindoline-5-sulfonamide-based acyl CoA:monoacylglycerol acyltransferase-2 inhibitors: Mitigation of CYP3A4 time-dependent inhibition and phototoxic liabilities.

Sato K, Takahagi H, Kubo O, Hidaka K, Yoshikawa T, Kamaura M, Nakakariya M, Amano N, Adachi R, Maki T, Take K, Takekawa S, Kitazaki T, Maekawa T. Sato K, et al. Among authors: take k. Bioorg Med Chem. 2015 Aug 1;23(15):4544-4560. doi: 10.1016/j.bmc.2015.06.003. Epub 2015 Jun 9. Bioorg Med Chem. 2015. PMID: 26100443

3

Pharmacological Inhibition of Monoacylglycerol O-Acyltransferase 2 Improves Hyperlipidemia, Obesity, and Diabetes by Change in Intestinal Fat Utilization.

Take K, Mochida T, Maki T, Satomi Y, Hirayama M, Nakakariya M, Amano N, Adachi R, Sato K, Kitazaki T, Takekawa S. Take K, et al. PLoS One. 2016 Mar 3;11(3):e0150976. doi: 10.1371/journal.pone.0150976. eCollection 2016. PLoS One. 2016. PMID: 26938273 Free PMC article.

4

Agents for the treatment of overactive detrusor. I. Synthesis and structure-activity relationships of 1,1'-biphenyl derivatives.

Take K, Okumura K, Takimoto K, Kato M, Ohtsuka M, Shiokawa Y. Take K, et al. Chem Pharm Bull (Tokyo). 1991 Nov;39(11):2915-23. doi: 10.1248/cpb.39.2915. Chem Pharm Bull (Tokyo). 1991. PMID: 1799939

5

Agents for the treatment of overactive detrusor. II. Synthesis and inhibitory activity on detrusor contraction of 1,1'-biphenyl-2,6-dicarboxylic acid diesters with an aminoalkyl group in the ester function.

Take K, Okumura K, Takimoto K, Ohtsuka M, Shiokawa Y. Take K, et al. Chem Pharm Bull (Tokyo). 1992 Apr;40(4):899-906. doi: 10.1248/cpb.40.899. Chem Pharm Bull (Tokyo). 1992. PMID: 1525946

6

Agents for the treatment of overactive detrusor. VI. Synthesis and pharmacological properties of acetamide derivatives bearing cyclic amines in N-substituents.

Taniguchi K, Tsubaki K, Mizuno H, Take K, Okumura K, Terai T, Shiokawa Y. Taniguchi K, et al. Among authors: take k. Chem Pharm Bull (Tokyo). 1994 Jan;42(1):74-84. doi: 10.1248/cpb.42.74. Chem Pharm Bull (Tokyo). 1994. PMID: 8124770

7

Agents for the treatment of overactive detrusor. VII. Synthesis and pharmacological properties of 2,3- and 3,4-diphenylcyclopentylamines, 2,3-diphenyl-2-cyclopentenylamines, and related compounds.

Taniguchi K, Tsubaki K, Take K, Okumura K, Terai T, Shiokawa Y. Taniguchi K, et al. Among authors: take k. Chem Pharm Bull (Tokyo). 1994 Apr;42(4):896-902. doi: 10.1248/cpb.42.896. Chem Pharm Bull (Tokyo). 1994. PMID: 8020125

8

Agents for the treatment of overactive detrusor. III. Synthesis and structure-activity relationships of N-(4-amino-2-butynyl)acetamide derivatives.

Take K, Okumura K, Tsubaki K, Terai T, Shiokawa Y. Take K, et al. Chem Pharm Bull (Tokyo). 1992 Jun;40(6):1415-23. doi: 10.1248/cpb.40.1415. Chem Pharm Bull (Tokyo). 1992. PMID: 1394662

9

Agents for the treatment of overactive detrusor. VIII. Synthesis and pharmacological properties of 4,4-diphenyl-2-cycloalkenylamines including FK584 and 3,3- or 4,4-diphenylcycloalkylamines.

Taniguchi K, Okumura K, Take K, Tsubaki K, Terai T, Nakanishi I, Shiokawa Y. Taniguchi K, et al. Among authors: take k. Chem Pharm Bull (Tokyo). 1995 Jan;43(1):71-7. doi: 10.1248/cpb.43.71. Chem Pharm Bull (Tokyo). 1995. PMID: 7895309

10

Agents for the treatment of overactive detrusor. IV. Synthesis and structure-activity relationships of cyclic analogues of terodiline.

Take K, Okumura K, Tsubaki K, Terai T, Shiokawa Y. Take K, et al. Chem Pharm Bull (Tokyo). 1993 Mar;41(3):507-15. doi: 10.1248/cpb.41.507. Chem Pharm Bull (Tokyo). 1993. PMID: 8477501

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