Yang KW - Search Results

1

Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice.

Scarneo SA, Eibschutz LS, Bendele PJ, Yang KW, Totzke J, Hughes P, Fox DA, Haystead TAJ. Scarneo SA, et al. Among authors: yang kw. Arthritis Res Ther. 2019 Dec 17;21(1):292. doi: 10.1186/s13075-019-2073-x. Arthritis Res Ther. 2019. PMID: 31847895 Free PMC article.

2

A highly selective inhibitor of interleukin-1 receptor-associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase.

Scarneo SA, Hughes PF, Yang KW, Carlson DA, Gurbani D, Westover KD, Haystead TAJ. Scarneo SA, et al. Among authors: yang kw. J Biol Chem. 2020 Feb 7;295(6):1565-1574. doi: 10.1074/jbc.RA119.011857. Epub 2019 Dec 30. J Biol Chem. 2020. PMID: 31914413 Free PMC article.

3

TAK1 regulates the tumor microenvironment through inflammatory, angiogenetic and apoptotic signaling cascades.

Scarneo SA, Yang KW, Roques JR, Dai A, Eibschutz LS, Hughes P, Haystead TAJ. Scarneo SA, et al. Among authors: yang kw. Oncotarget. 2020 May 26;11(21):1961-1970. doi: 10.18632/oncotarget.27606. eCollection 2020 May 26. Oncotarget. 2020. PMID: 32523651 Free PMC article.

4

TAK1: a potent tumour necrosis factor inhibitor for the treatment of inflammatory diseases.

Totzke J, Scarneo SA, Yang KW, Haystead TAJ. Totzke J, et al. Among authors: yang kw. Open Biol. 2020 Sep;10(9):200099. doi: 10.1098/rsob.200099. Epub 2020 Sep 2. Open Biol. 2020. PMID: 32873150 Free PMC article. Review.

5

[No title available]

[No authors listed] [No authors listed] PMID: 33485548

6

Expression of ectopic heat shock protein 90 in male and female primary afferent nociceptors regulates inflammatory pain.

Wang Y, Scarneo SA, Kim SH, Zhang X, Chen J, Yang KW, Hughes P, Haystead T, Nackley AG. Wang Y, et al. Among authors: yang kw. Pain. 2022 Jun 1;163(6):1091-1101. doi: 10.1097/j.pain.0000000000002511. Epub 2021 Oct 12. Pain. 2022. PMID: 34995041 Free PMC article.

7

Development and Efficacy of an Orally Bioavailable Selective TAK1 Inhibitor for the Treatment of Inflammatory Arthritis.

Scarneo S, Hughes P, Freeze R, Yang K, Totzke J, Haystead T. Scarneo S, et al. ACS Chem Biol. 2022 Mar 18;17(3):536-544. doi: 10.1021/acschembio.1c00788. Epub 2022 Mar 2. ACS Chem Biol. 2022. PMID: 35234444 Free PMC article.

8

Expression of membrane Hsp90 is a molecular signature of T cell activation.

Scarneo SA, Smith AP, Favret J, O'Connell R, Pickeral J, Yang KW, Ferrari G, Loiselle DR, Hughes PF, Kulkarni MM, Gargesha M, Scott B, Roy D, Haynes BF, Kwiek JJ, Haystead TAJ. Scarneo SA, et al. Among authors: yang kw. Sci Rep. 2022 Oct 27;12(1):18091. doi: 10.1038/s41598-022-22788-8. Sci Rep. 2022. PMID: 36302951 Free PMC article.

9

Delineation of the distinct inflammatory signaling roles of TAK1 and JAK1/3 in the CIA model of rheumatoid arthritis.

Freeze R, Yang KW, Haystead T, Hughes P, Scarneo S. Freeze R, et al. Among authors: yang kw. Pharmacol Res Perspect. 2023 Aug;11(4):e01124. doi: 10.1002/prp2.1124. Pharmacol Res Perspect. 2023. PMID: 37564034 Free PMC article.

10

Patterns of healthcare utilization according to health equity determinants during the first year of the pandemic at Johns Hopkins Medicine.

Yang KK, Rattsev I, Lkhagvajav Z, Flaks-Manov N, Gorman K, Epstein JA, Crainiceanu CM, Taylor CO. Yang KK, et al. JAMIA Open. 2024 Oct 7;7(4):ooae093. doi: 10.1093/jamiaopen/ooae093. eCollection 2024 Dec. JAMIA Open. 2024. PMID: 39386066 Free PMC article.

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