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Association of Prehospital Plasma Transfusion With Survival in Trauma Patients With Hemorrhagic Shock When Transport Times Are Longer Than 20 Minutes: A Post Hoc Analysis of the PAMPer and COMBAT Clinical Trials.
Pusateri AE, Moore EE, Moore HB, Le TD, Guyette FX, Chapman MP, Sauaia A, Ghasabyan A, Chandler J, McVaney K, Brown JB, Daley BJ, Miller RS, Harbrecht BG, Claridge JA, Phelan HA, Witham WR, Putnam AT, Sperry JL. Pusateri AE, et al. Among authors: ghasabyan a. JAMA Surg. 2020 Feb 1;155(2):e195085. doi: 10.1001/jamasurg.2019.5085. Epub 2020 Feb 19. JAMA Surg. 2020. PMID: 31851290 Free PMC article. Clinical Trial.
Platelets are dominant contributors to hypercoagulability after injury.
Harr JN, Moore EE, Chin TL, Ghasabyan A, Gonzalez E, Wohlauer MV, Banerjee A, Silliman CC, Sauaia A. Harr JN, et al. Among authors: ghasabyan a. J Trauma Acute Care Surg. 2013 Mar;74(3):756-62; discussion 762-5. doi: 10.1097/TA.0b013e3182826d7e. J Trauma Acute Care Surg. 2013. PMID: 23425732 Free PMC article. Clinical Trial.
Viscoelastic hemostatic fibrinogen assays detect fibrinolysis early.
Harr JN, Moore EE, Chin TL, Chapman MP, Ghasabyan A, Stringham JR, Banerjee A, Silliman CC. Harr JN, et al. Among authors: ghasabyan a. Eur J Trauma Emerg Surg. 2015 Feb;41(1):49-56. doi: 10.1007/s00068-014-0400-0. Epub 2014 Apr 4. Eur J Trauma Emerg Surg. 2015. PMID: 26038165 Free PMC article.
The "Death Diamond": Rapid thrombelastography identifies lethal hyperfibrinolysis.
Chapman MP, Moore EE, Moore HB, Gonzalez E, Morton AP, Chandler J, Fleming CD, Ghasabyan A, Silliman CC, Banerjee A, Sauaia A. Chapman MP, et al. Among authors: ghasabyan a. J Trauma Acute Care Surg. 2015 Dec;79(6):925-9. doi: 10.1097/TA.0000000000000871. J Trauma Acute Care Surg. 2015. PMID: 26488324 Free PMC article.
Overwhelming tPA release, not PAI-1 degradation, is responsible for hyperfibrinolysis in severely injured trauma patients.
Chapman MP, Moore EE, Moore HB, Gonzalez E, Gamboni F, Chandler JG, Mitra S, Ghasabyan A, Chin TL, Sauaia A, Banerjee A, Silliman CC. Chapman MP, et al. Among authors: ghasabyan a. J Trauma Acute Care Surg. 2016 Jan;80(1):16-23; discussion 23-5. doi: 10.1097/TA.0000000000000885. J Trauma Acute Care Surg. 2016. PMID: 26491796 Free PMC article.
35 results