Zhu Y - Search Results

1

Novel 2, 5-diketopiperazine derivatives as potent selective histone deacetylase 6 inhibitors: Rational design, synthesis and antiproliferative activity.

Chen X, Chen X, Steimbach RR, Wu T, Li H, Dan W, Shi P, Cao C, Li D, Miller AK, Qiu Z, Gao J, Zhu Y. Chen X, et al. Among authors: zhu y. Eur J Med Chem. 2020 Feb 1;187:111950. doi: 10.1016/j.ejmech.2019.111950. Epub 2019 Dec 6. Eur J Med Chem. 2020. PMID: 31865013

2

Investigation on the isoform selectivity of histone deacetylase inhibitors using chemical feature based pharmacophore and docking approaches.

Zhu Y, Li HF, Lu S, Zheng YX, Wu Z, Tang WF, Zhou X, Lu T. Zhu Y, et al. Eur J Med Chem. 2010 May;45(5):1777-91. doi: 10.1016/j.ejmech.2010.01.010. Epub 2010 Jan 28. Eur J Med Chem. 2010. PMID: 20153566

3

Design, synthesis and biological evaluation of β-carboline derivatives as novel inhibitors targeting B-Raf kinase.

Xin B, Tang W, Wang Y, Lin G, Liu H, Jiao Y, Zhu Y, Yuan H, Chen Y, Lu T. Xin B, et al. Among authors: zhu y. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4783-6. doi: 10.1016/j.bmcl.2012.05.053. Epub 2012 May 24. Bioorg Med Chem Lett. 2012. PMID: 22704238

4

Synthesis and antitumor activity of novel diaryl ether hydroxamic acids derivatives as potential HDAC inhibitors.

Zhu Y, Chen X, Wu Z, Zheng Y, Chen Y, Tang W, Lu T. Zhu Y, et al. Arch Pharm Res. 2012 Oct;35(10):1723-32. doi: 10.1007/s12272-012-1003-0. Epub 2012 Nov 9. Arch Pharm Res. 2012. PMID: 23139122

5

Synthesis and Biological Evaluation of 1-(2-Aminophenyl)-3-arylurea Derivatives as Potential EphA2 and HDAC Dual Inhibitors.

Zhu Y, Ran T, Chen X, Niu J, Zhao S, Lu T, Tang W. Zhu Y, et al. Chem Pharm Bull (Tokyo). 2016;64(8):1136-41. doi: 10.1248/cpb.c16-00154. Chem Pharm Bull (Tokyo). 2016. PMID: 27477652 Free article.

6

Design, synthesis and biological evaluation of novel isoindolinone derivatives as potent histone deacetylase inhibitors.

Chen X, Zhao S, Li H, Wang X, Geng A, Cui H, Lu T, Chen Y, Zhu Y. Chen X, et al. Among authors: zhu y. Eur J Med Chem. 2019 Apr 15;168:110-122. doi: 10.1016/j.ejmech.2019.02.032. Epub 2019 Feb 14. Eur J Med Chem. 2019. PMID: 30802729

7

Discovery of novel phenoxybenzamide analogues as Raf/HDAC dual inhibitors.

Geng A, Cui H, Zhang L, Chen X, Li H, Lu T, Zhu Y. Geng A, et al. Among authors: zhu y. Bioorg Med Chem Lett. 2019 Jul 1;29(13):1605-1608. doi: 10.1016/j.bmcl.2019.04.047. Epub 2019 Apr 29. Bioorg Med Chem Lett. 2019. PMID: 31053508

8

Design, Synthesis and Biological Evaluation of Novel Benzoylimidazole Derivatives as Raf and Histone Deacetylases Dual Inhibitors.

Chen X, Gong G, Chen X, Song R, Duan M, Qiao R, Jiao Y, Qi J, Chen Y, Zhu Y. Chen X, et al. Among authors: zhu y. Chem Pharm Bull (Tokyo). 2019;67(10):1116-1122. doi: 10.1248/cpb.c19-00425. Chem Pharm Bull (Tokyo). 2019. PMID: 31582631 Free article.

9

Design and synthesis of HDAC inhibitors to enhance the therapeutic effect of diffuse large B-cell lymphoma by improving metabolic stability and pharmacokinetic characteristics.

Cui H, Hong Q, Wei R, Li H, Wan C, Chen X, Zhao S, Bu H, Zhang B, Yang D, Lu T, Chen Y, Zhu Y. Cui H, et al. Among authors: zhu y. Eur J Med Chem. 2022 Feb 5;229:114049. doi: 10.1016/j.ejmech.2021.114049. Epub 2021 Dec 18. Eur J Med Chem. 2022. PMID: 34954594

10

Design and synthesis of dual inhibitors targeting snail and histone deacetylase for the treatment of solid tumour cancer.

Cui H, Huang J, Lei Y, Chen Q, Hu Z, Niu J, Wei R, Yang K, Li H, Lu T, Zhu Y, Huang Y. Cui H, et al. Among authors: zhu y. Eur J Med Chem. 2022 Feb 5;229:114082. doi: 10.1016/j.ejmech.2021.114082. Epub 2021 Dec 30. Eur J Med Chem. 2022. PMID: 34995925

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