Prasad R - Search Results

1

In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains.

Orofino F, Truglio GI, Fiorucci D, D'Agostino I, Borgini M, Poggialini F, Zamperini C, Dreassi E, Maccari L, Torelli R, Martini C, Bernabei M, Meis JF, Khandelwal NK, Prasad R, Sanguinetti M, Bugli F, Botta M. Orofino F, et al. Among authors: prasad r. Int J Antimicrob Agents. 2020 Mar;55(3):105865. doi: 10.1016/j.ijantimicag.2019.105865. Epub 2019 Dec 20. Int J Antimicrob Agents. 2020. PMID: 31866465

2

In vitro low-level resistance to azoles in Candida albicans is associated with changes in membrane lipid fluidity and asymmetry.

Kohli A, Smriti, Mukhopadhyay K, Rattan A, Prasad R. Kohli A, et al. Among authors: prasad r. Antimicrob Agents Chemother. 2002 Apr;46(4):1046-52. doi: 10.1128/AAC.46.4.1046-1052.2002. Antimicrob Agents Chemother. 2002. PMID: 11897588 Free PMC article.

3

Drug susceptibilities of yeast cells are affected by membrane lipid composition.

Mukhopadhyay K, Kohli A, Prasad R. Mukhopadhyay K, et al. Among authors: prasad r. Antimicrob Agents Chemother. 2002 Dec;46(12):3695-705. doi: 10.1128/AAC.46.12.3695-3705.2002. Antimicrob Agents Chemother. 2002. PMID: 12435664 Free PMC article.

4

Membrane sphingolipid-ergosterol interactions are important determinants of multidrug resistance in Candida albicans.

Mukhopadhyay K, Prasad T, Saini P, Pucadyil TJ, Chattopadhyay A, Prasad R. Mukhopadhyay K, et al. Among authors: prasad t, prasad r. Antimicrob Agents Chemother. 2004 May;48(5):1778-87. doi: 10.1128/AAC.48.5.1778-1787.2004. Antimicrob Agents Chemother. 2004. PMID: 15105135 Free PMC article.

5

Substitution of threonine-1351 in the multidrug transporter Cdr1p of Candida albicans results in hypersusceptibility to antifungal agents and threonine-1351 is essential for synergic effects of calcineurin inhibitor FK520.

Shukla S, Ambudkar SV, Prasad R. Shukla S, et al. Among authors: prasad r. J Antimicrob Chemother. 2004 Jul;54(1):38-45. doi: 10.1093/jac/dkh308. Epub 2004 Jun 9. J Antimicrob Chemother. 2004. PMID: 15190023

6

Multidrug resistance in yeast Candida.

Prasad R, Kapoor K. Prasad R, et al. Int Rev Cytol. 2005;242:215-48. doi: 10.1016/S0074-7696(04)42005-1. Int Rev Cytol. 2005. PMID: 15598470 Review.

7

Functional analysis of CaIPT1, a sphingolipid biosynthetic gene involved in multidrug resistance and morphogenesis of Candida albicans.

Prasad T, Saini P, Gaur NA, Vishwakarma RA, Khan LA, Haq QM, Prasad R. Prasad T, et al. Among authors: prasad r. Antimicrob Agents Chemother. 2005 Aug;49(8):3442-52. doi: 10.1128/AAC.49.8.3442-3452.2005. Antimicrob Agents Chemother. 2005. PMID: 16048959 Free PMC article.

8

Unexpected link between iron and drug resistance of Candida spp.: iron depletion enhances membrane fluidity and drug diffusion, leading to drug-susceptible cells.

Prasad T, Chandra A, Mukhopadhyay CK, Prasad R. Prasad T, et al. Among authors: prasad r. Antimicrob Agents Chemother. 2006 Nov;50(11):3597-606. doi: 10.1128/AAC.00653-06. Epub 2006 Sep 5. Antimicrob Agents Chemother. 2006. PMID: 16954314 Free PMC article.

9

Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.

Pasrija R, Panwar SL, Prasad R. Pasrija R, et al. Among authors: prasad r. Antimicrob Agents Chemother. 2008 Feb;52(2):694-704. doi: 10.1128/AAC.00861-07. Epub 2007 Dec 3. Antimicrob Agents Chemother. 2008. PMID: 18056285 Free PMC article.

10

Transcriptional activation and increased mRNA stability contribute to overexpression of CDR1 in azole-resistant Candida albicans.

Manoharlal R, Gaur NA, Panwar SL, Morschhäuser J, Prasad R. Manoharlal R, et al. Among authors: prasad r. Antimicrob Agents Chemother. 2008 Apr;52(4):1481-92. doi: 10.1128/AAC.01106-07. Epub 2008 Feb 11. Antimicrob Agents Chemother. 2008. PMID: 18268086 Free PMC article.

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