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Impact of spaceflight on the murine thymus and mitigation by exposure to artificial gravity during spaceflight.
Horie K, Kato T, Kudo T, Sasanuma H, Miyauchi M, Akiyama N, Miyao T, Seki T, Ishikawa T, Takakura Y, Shirakawa M, Shiba D, Hamada M, Jeon H, Yoshida N, Inoue JI, Muratani M, Takahashi S, Ohno H, Akiyama T. Horie K, et al. Among authors: miyao t. Sci Rep. 2019 Dec 27;9(1):19866. doi: 10.1038/s41598-019-56432-9. Sci Rep. 2019. PMID: 31882694 Free PMC article.
Long-term hindlimb unloading causes a preferential reduction of medullary thymic epithelial cells expressing autoimmune regulator (Aire).
Horie K, Kudo T, Yoshinaga R, Akiyama N, Sasanuma H, Kobayashi TJ, Shimbo M, Jeon H, Miyao T, Miyauchi M, Shirakawa M, Shiba D, Yoshida N, Muratani M, Takahashi S, Akiyama T. Horie K, et al. Among authors: miyao t. Biochem Biophys Res Commun. 2018 Jun 27;501(3):745-750. doi: 10.1016/j.bbrc.2018.05.060. Biochem Biophys Res Commun. 2018. PMID: 29753741
The CCR4-NOT deadenylase complex safeguards thymic positive selection by down-regulating aberrant pro-apoptotic gene expression.
Ito-Kureha T, Miyao T, Nishijima S, Suzuki T, Koizumi SI, Villar-Briones A, Takahashi A, Akiyama N, Morita M, Naguro I, Ishikawa H, Ichijo H, Akiyama T, Yamamoto T. Ito-Kureha T, et al. Among authors: miyao t. Nat Commun. 2020 Dec 2;11(1):6169. doi: 10.1038/s41467-020-19975-4. Nat Commun. 2020. PMID: 33268794 Free PMC article.
Integrative analysis of scRNA-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator.
Miyao T, Miyauchi M, Kelly ST, Terooatea TW, Ishikawa T, Oh E, Hirai S, Horie K, Takakura Y, Ohki H, Hayama M, Maruyama Y, Seki T, Ishii H, Yabukami H, Yoshida M, Inoue A, Sakaue-Sawano A, Miyawaki A, Muratani M, Minoda A, Akiyama N, Akiyama T. Miyao T, et al. Elife. 2022 May 17;11:e73998. doi: 10.7554/eLife.73998. Elife. 2022. PMID: 35578835 Free PMC article.
Acute irradiation causes a long-term disturbance in the heterogeneity and gene expression profile of medullary thymic epithelial cells.
Horie K, Namiki K, Kinoshita K, Miyauchi M, Ishikawa T, Hayama M, Maruyama Y, Hagiwara N, Miyao T, Murata S, Kobayashi TJ, Akiyama N, Akiyama T. Horie K, et al. Among authors: miyao t. Front Immunol. 2023 Nov 2;14:1186154. doi: 10.3389/fimmu.2023.1186154. eCollection 2023. Front Immunol. 2023. PMID: 38022666 Free PMC article.
110 results