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Page 1
Mass Spectrometry Reveals the Direct Action of a Chemical Chaperone.
Gault J, Lianoudaki D, Kaldmäe M, Kronqvist N, Rising A, Johansson J, Lohkamp B, Laín S, Allison TM, Lane DP, Marklund EG, Landreh M. Gault J, et al. Among authors: lane dp. J Phys Chem Lett. 2018 Jul 19;9(14):4082-4086. doi: 10.1021/acs.jpclett.8b01817. Epub 2018 Jul 9. J Phys Chem Lett. 2018. PMID: 29975538 Free article.
High intracellular stability of the spidroin N-terminal domain in spite of abundant amyloidogenic segments revealed by in-cell hydrogen/deuterium exchange mass spectrometry.
Kaldmäe M, Leppert A, Chen G, Sarr M, Sahin C, Nordling K, Kronqvist N, Gonzalvo-Ulla M, Fritz N, Abelein A, Laίn S, Biverstål H, Jörnvall H, Lane DP, Rising A, Johansson J, Landreh M. Kaldmäe M, et al. Among authors: lane dp. FEBS J. 2020 Jul;287(13):2823-2833. doi: 10.1111/febs.15169. Epub 2019 Dec 20. FEBS J. 2020. PMID: 31815338 Free PMC article.
Combining native and 'omics' mass spectrometry to identify endogenous ligands bound to membrane proteins.
Gault J, Liko I, Landreh M, Shutin D, Bolla JR, Jefferies D, Agasid M, Yen HY, Ladds MJGW, Lane DP, Khalid S, Mullen C, Remes PM, Huguet R, McAlister G, Goodwin M, Viner R, Syka JEP, Robinson CV. Gault J, et al. Among authors: lane dp. Nat Methods. 2020 May;17(5):505-508. doi: 10.1038/s41592-020-0821-0. Epub 2020 May 4. Nat Methods. 2020. PMID: 32371966 Free PMC article.
A "spindle and thread" mechanism unblocks p53 translation by modulating N-terminal disorder.
Kaldmäe M, Vosselman T, Zhong X, Lama D, Chen G, Saluri M, Kronqvist N, Siau JW, Ng AS, Ghadessy FJ, Sabatier P, Vojtesek B, Sarr M, Sahin C, Österlund N, Ilag LL, Väänänen VA, Sedimbi S, Arsenian-Henriksson M, Zubarev RA, Nilsson L, Koeck PJB, Rising A, Abelein A, Fritz N, Johansson J, Lane DP, Landreh M. Kaldmäe M, et al. Among authors: lane dp. Structure. 2022 May 5;30(5):733-742.e7. doi: 10.1016/j.str.2022.02.013. Epub 2022 Mar 14. Structure. 2022. PMID: 35290795 Free article.
Covalent Rescue of Mutant p53.
Lane DP, Verma CS. Lane DP, et al. Cancer Discov. 2023 Jan 9;13(1):14-16. doi: 10.1158/2159-8290.CD-22-1212. Cancer Discov. 2023. PMID: 36620883
Benzene Probes in Molecular Dynamics Simulations Reveal Novel Binding Sites for Ligand Design.
Tan YS, Reeks J, Brown CJ, Thean D, Ferrer Gago FJ, Yuen TY, Goh ET, Lee XE, Jennings CE, Joseph TL, Lakshminarayanan R, Lane DP, Noble ME, Verma CS. Tan YS, et al. Among authors: lane dp. J Phys Chem Lett. 2016 Sep 1;7(17):3452-7. doi: 10.1021/acs.jpclett.6b01525. Epub 2016 Aug 22. J Phys Chem Lett. 2016. PMID: 27532490 Free PMC article.
500 results