Datti A - Search Results

1

ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway.

Moskal N, Riccio V, Bashkurov M, Taddese R, Datti A, Lewis PN, Angus McQuibban G. Moskal N, et al. Among authors: datti a. Nat Commun. 2020 Jan 3;11(1):88. doi: 10.1038/s41467-019-13781-3. Nat Commun. 2020. PMID: 31900402 Free PMC article.

2

Excess Polθ functions in response to replicative stress in homologous recombination-proficient cancer cells.

Goullet de Rugy T, Bashkurov M, Datti A, Betous R, Guitton-Sert L, Cazaux C, Durocher D, Hoffmann JS. Goullet de Rugy T, et al. Among authors: datti a. Biol Open. 2016 Oct 15;5(10):1485-1492. doi: 10.1242/bio.018028. Biol Open. 2016. PMID: 27612511 Free PMC article.

3

A drug discovery platform to identify compounds that inhibit EGFR triple mutants.

Saraon P, Snider J, Kalaidzidis Y, Wybenga-Groot LE, Weiss K, Rai A, Radulovich N, Drecun L, Vučković N, Vučetić A, Wong V, Thériault B, Pham NA, Park JH, Datti A, Wang J, Pathmanathan S, Aboualizadeh F, Lyakisheva A, Yao Z, Wang Y, Joseph B, Aman A, Moran MF, Prakesch M, Poda G, Marcellus R, Uehling D, Samaržija M, Jakopović M, Tsao MS, Shepherd FA, Sacher A, Leighl N, Akhmanova A, Al-Awar R, Zerial M, Stagljar I. Saraon P, et al. Among authors: datti a. Nat Chem Biol. 2020 May;16(5):577-586. doi: 10.1038/s41589-020-0484-2. Epub 2020 Feb 24. Nat Chem Biol. 2020. PMID: 32094923 Free PMC article.

4

High-throughput sensitive screening of small molecule modulators of microexon alternative splicing using dual Nano and Firefly luciferase reporters.

Best AJ, Braunschweig U, Wu M, Farhangmehr S, Pasculescu A, Lim JJ, Comsa LC, Jen M, Wang J, Datti A, Wrana JL, Cordes SP, Al-Awar R, Han H, Blencowe BJ. Best AJ, et al. Among authors: datti a. Nat Commun. 2024 Jul 27;15(1):6328. doi: 10.1038/s41467-024-50399-6. Nat Commun. 2024. PMID: 39068192 Free PMC article.

5

Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway.

Miller BW, Lau G, Grouios C, Mollica E, Barrios-Rodiles M, Liu Y, Datti A, Morris Q, Wrana JL, Attisano L. Miller BW, et al. Among authors: datti a. Mol Syst Biol. 2009;5:315. doi: 10.1038/msb.2009.72. Epub 2009 Oct 13. Mol Syst Biol. 2009. PMID: 19888210 Free PMC article.

6

Cell-based high-throughput screen for small molecule inhibitors of Bax translocation.

Hui KK, Dojo Soeandy C, Chang S, Vizeacoumar FS, Sun T, Datti A, Henderson JT. Hui KK, et al. Among authors: datti a. J Cell Mol Med. 2019 Mar;23(3):1784-1797. doi: 10.1111/jcmm.14076. Epub 2018 Dec 13. J Cell Mol Med. 2019. PMID: 30548903 Free PMC article.

7

Digitoxin-induced cytotoxicity in cancer cells is mediated through distinct kinase and interferon signaling networks.

Prassas I, Karagiannis GS, Batruch I, Dimitromanolakis A, Datti A, Diamandis EP. Prassas I, et al. Among authors: datti a. Mol Cancer Ther. 2011 Nov;10(11):2083-93. doi: 10.1158/1535-7163.MCT-11-0421. Epub 2011 Aug 22. Mol Cancer Ther. 2011. PMID: 21859838

8

Ibrutinib synergizes with poly(ADP-ribose) glycohydrolase inhibitors to induce cell death in AML cells via a BTK-independent mechanism.

Rotin LE, Gronda M, MacLean N, Hurren R, Wang X, Lin FH, Wrana J, Datti A, Barber DL, Minden MD, Slassi M, Schimmer AD. Rotin LE, et al. Among authors: datti a. Oncotarget. 2016 Jan 19;7(3):2765-79. doi: 10.18632/oncotarget.6409. Oncotarget. 2016. PMID: 26624983 Free PMC article.

9

High-throughput drug library screening identifies colchicine as a thyroid cancer inhibitor.

Zhang L, Yang Z, Granieri L, Pasculescu A, Datti A, Asa SL, Xu Z, Ezzat S. Zhang L, et al. Among authors: datti a. Oncotarget. 2016 Apr 12;7(15):19948-59. doi: 10.18632/oncotarget.7890. Oncotarget. 2016. PMID: 26942566 Free PMC article.

10

Erlotinib synergizes with the poly(ADP-ribose) glycohydrolase inhibitor ethacridine in acute myeloid leukemia cells.

Rotin LE, MacLean N, Aman A, Gronda M, Lin FH, Hurren R, Wang X, Wrana JL, Datti A, Al-Awar R, Minden MD, Schimmer AD. Rotin LE, et al. Among authors: datti a. Haematologica. 2016 Nov;101(11):e449-e453. doi: 10.3324/haematol.2016.146894. Epub 2016 Sep 1. Haematologica. 2016. PMID: 27587383 Free PMC article. No abstract available.

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