Raunio H - Search Results

1

In vitro sulfonation of 7-hydroxycoumarin derivatives in liver cytosol of human and six animal species.

Juvonen RO, Pentikäinen O, Huuskonen J, Timonen J, Kärkkäinen O, Heikkinen A, Fashe M, Raunio H. Juvonen RO, et al. Among authors: raunio h. Xenobiotica. 2020 Aug;50(8):885-893. doi: 10.1080/00498254.2020.1711544. Epub 2020 Jan 8. Xenobiotica. 2020. PMID: 31903849 Free PMC article.

2

Inhibitory effects and oxidation of 6-methylcoumarin, 7-methylcoumarin and 7-formylcoumarin via human CYP2A6 and its mouse and pig orthologous enzymes.

Juvonen RO, Kuusisto M, Fohrgrup C, Pitkänen MH, Nevalainen TJ, Auriola S, Raunio H, Pasanen M, Pentikäinen OT. Juvonen RO, et al. Among authors: raunio h. Xenobiotica. 2016;46(1):14-24. doi: 10.3109/00498254.2015.1048327. Epub 2015 Jun 11. Xenobiotica. 2016. PMID: 26068522

3

Development of new Coumarin-based profluorescent substrates for human cytochrome P450 enzymes.

Juvonen RO, Ahinko M, Huuskonen J, Raunio H, Pentikäinen OT. Juvonen RO, et al. Among authors: raunio h. Xenobiotica. 2019 Sep;49(9):1015-1024. doi: 10.1080/00498254.2018.1530399. Epub 2018 Nov 29. Xenobiotica. 2019. PMID: 30272491

4

In vitro glucuronidation of 7-hydroxycoumarin derivatives in intestine and liver microsomes of Beagle dogs.

Juvonen RO, Heikkinen AT, Kärkkäinen O, Jehangir R, Huuskonen J, Troberg J, Raunio H, Pentikäinen OT, Finel M. Juvonen RO, et al. Among authors: raunio h. Eur J Pharm Sci. 2020 Jan 1;141:105118. doi: 10.1016/j.ejps.2019.105118. Epub 2019 Oct 25. Eur J Pharm Sci. 2020. PMID: 31669387

5

Molecular docking and oxidation kinetics of 3-phenyl coumarin derivatives by human CYP2A13.

Juvonen RO, Jokinen EM, Huuskonen J, Kärkkäinen O, Raunio H, Pentikäinen OT. Juvonen RO, et al. Among authors: raunio h. Xenobiotica. 2021 Nov;51(11):1207-1216. doi: 10.1080/00498254.2021.1898700. Epub 2021 Nov 2. Xenobiotica. 2021. PMID: 33703988 Free article.

6

Comparison of In Vitro Hepatic Scoparone 7-O-Demethylation between Humans and Experimental Animals.

Fayyaz A, Makwinja S, Auriola S, Raunio H, Juvonen RO. Fayyaz A, et al. Among authors: raunio h. Planta Med. 2018 Mar;84(5):320-328. doi: 10.1055/s-0043-119886. Epub 2017 Sep 26. Planta Med. 2018. PMID: 28950382

7

Molecular Docking-Based Design and Development of a Highly Selective Probe Substrate for UDP-glucuronosyltransferase 1A10.

Juvonen RO, Rauhamäki S, Kortet S, Niinivehmas S, Troberg J, Petsalo A, Huuskonen J, Raunio H, Finel M, Pentikäinen OT. Juvonen RO, et al. Among authors: raunio h. Mol Pharm. 2018 Mar 5;15(3):923-933. doi: 10.1021/acs.molpharmaceut.7b00871. Epub 2018 Feb 15. Mol Pharm. 2018. PMID: 29421866 Free PMC article.

8

Metabolism of Scoparone in Experimental Animals and Humans.

Juvonen RO, Novák F, Emmanouilidou E, Auriola S, Timonen J, Heikkinen AT, Küblbeck J, Finel M, Raunio H. Juvonen RO, et al. Among authors: raunio h. Planta Med. 2019 Apr;85(6):453-464. doi: 10.1055/a-0835-2301. Epub 2019 Feb 8. Planta Med. 2019. PMID: 30736072

9

Coumarin-Based Profluorescent and Fluorescent Substrates for Determining Xenobiotic-Metabolizing Enzyme Activities In Vitro.

Raunio H, Pentikäinen O, Juvonen RO. Raunio H, et al. Int J Mol Sci. 2020 Jul 1;21(13):4708. doi: 10.3390/ijms21134708. Int J Mol Sci. 2020. PMID: 32630278 Free PMC article. Review.

10

Substrate Selectivity of Coumarin Derivatives by Human CYP1 Enzymes: In Vitro Enzyme Kinetics and In Silico Modeling.

Juvonen RO, Ahinko M, Jokinen EM, Huuskonen J, Raunio H, Pentikäinen OT. Juvonen RO, et al. Among authors: raunio h. ACS Omega. 2021 Apr 19;6(17):11286-11296. doi: 10.1021/acsomega.1c00123. eCollection 2021 May 4. ACS Omega. 2021. PMID: 34056284 Free PMC article.

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