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Multiregion exome sequencing of ovarian immature teratomas reveals 2N near-diploid genomes, paucity of somatic mutations, and extensive allelic imbalances shared across mature, immature, and disseminated components.
Heskett MB, Sanborn JZ, Boniface C, Goode B, Chapman J, Garg K, Rabban JT, Zaloudek C, Benz SC, Spellman PT, Solomon DA, Cho RJ. Heskett MB, et al. Among authors: spellman pt. Mod Pathol. 2020 Jun;33(6):1193-1206. doi: 10.1038/s41379-019-0446-y. Epub 2020 Jan 7. Mod Pathol. 2020. PMID: 31911616 Free PMC article.
Temporal dissection of tumorigenesis in primary cancers.
Durinck S, Ho C, Wang NJ, Liao W, Jakkula LR, Collisson EA, Pons J, Chan SW, Lam ET, Chu C, Park K, Hong SW, Hur JS, Huh N, Neuhaus IM, Yu SS, Grekin RC, Mauro TM, Cleaver JE, Kwok PY, LeBoit PE, Getz G, Cibulskis K, Aster JC, Huang H, Purdom E, Li J, Bolund L, Arron ST, Gray JW, Spellman PT, Cho RJ. Durinck S, et al. Among authors: spellman pt. Cancer Discov. 2011 Jul;1(2):137-43. doi: 10.1158/2159-8290.CD-11-0028. Epub 2011 Jun 29. Cancer Discov. 2011. PMID: 21984974 Free PMC article.
Transcription restores DNA repair to heterochromatin, determining regional mutation rates in cancer genomes.
Zheng CL, Wang NJ, Chung J, Moslehi H, Sanborn JZ, Hur JS, Collisson EA, Vemula SS, Naujokas A, Chiotti KE, Cheng JB, Fassihi H, Blumberg AJ, Bailey CV, Fudem GM, Mihm FG, Cunningham BB, Neuhaus IM, Liao W, Oh DH, Cleaver JE, LeBoit PE, Costello JF, Lehmann AR, Gray JW, Spellman PT, Arron ST, Huh N, Purdom E, Cho RJ. Zheng CL, et al. Among authors: spellman pt. Cell Rep. 2014 Nov 20;9(4):1228-34. doi: 10.1016/j.celrep.2014.10.031. Epub 2014 Nov 20. Cell Rep. 2014. PMID: 25456125 Free PMC article.
Erratum to: Modeling precision treatment of breast cancer.
Daemen A, Griffith OL, Heiser LM, Wang NJ, Enache OM, Sanborn Z, Pepin F, Durinck S, Korkola JE, Griffith M, Hur JS, Huh N, Chung J, Cope L, Fackler MJ, Umbricht C, Sukumar S, Seth P, Sukhatme VP, Jakkula LR, Lu Y, Mills GB, Cho RJ, Collisson EA, Van't Veer LJ, Spellman PT, Gray JW. Daemen A, et al. Among authors: spellman pt. Genome Biol. 2015 May 12;16(1):95. doi: 10.1186/s13059-015-0658-5. Genome Biol. 2015. PMID: 25962591 Free PMC article.
Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination.
Sanborn JZ, Chung J, Purdom E, Wang NJ, Kakavand H, Wilmott JS, Butler T, Thompson JF, Mann GJ, Haydu LE, Saw RP, Busam KJ, Lo RS, Collisson EA, Hur JS, Spellman PT, Cleaver JE, Gray JW, Huh N, Murali R, Scolyer RA, Bastian BC, Cho RJ. Sanborn JZ, et al. Among authors: spellman pt. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):10995-1000. doi: 10.1073/pnas.1508074112. Epub 2015 Aug 18. Proc Natl Acad Sci U S A. 2015. PMID: 26286987 Free PMC article.
Circulating tumor DNA dynamics using patient-customized assays are associated with outcome in neoadjuvantly treated breast cancer.
Butler TM, Boniface CT, Johnson-Camacho K, Tabatabaei S, Melendez D, Kelley T, Gray J, Corless CL, Spellman PT. Butler TM, et al. Among authors: spellman pt. Cold Spring Harb Mol Case Stud. 2019 Apr 1;5(2):a003772. doi: 10.1101/mcs.a003772. Print 2019 Apr. Cold Spring Harb Mol Case Stud. 2019. PMID: 30833418 Free PMC article.
The Feasibility of Patient-Specific Circulating Tumor DNA Monitoring throughout Multi-Modality Therapy for Locally Advanced Esophageal and Rectal Cancer: A Potential Biomarker for Early Detection of Subclinical Disease.
Boniface C, Deig C, Halsey C, Kelley T, Heskett MB, Thomas CR Jr, Spellman PT, Nabavizadeh N. Boniface C, et al. Among authors: spellman pt. Diagnostics (Basel). 2021 Jan 5;11(1):73. doi: 10.3390/diagnostics11010073. Diagnostics (Basel). 2021. PMID: 33466369 Free PMC article.
Differential Allelic Expression among Long Non-Coding RNAs.
Heskett MB, Spellman PT, Thayer MJ. Heskett MB, et al. Among authors: spellman pt. Noncoding RNA. 2021 Oct 22;7(4):66. doi: 10.3390/ncrna7040066. Noncoding RNA. 2021. PMID: 34698262 Free PMC article. Review.
An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer.
Johnson BE, Creason AL, Stommel JM, Keck JM, Parmar S, Betts CB, Blucher A, Boniface C, Bucher E, Burlingame E, Camp T, Chin K, Eng J, Estabrook J, Feiler HS, Heskett MB, Hu Z, Kolodzie A, Kong BL, Labrie M, Lee J, Leyshock P, Mitri S, Patterson J, Riesterer JL, Sivagnanam S, Somers J, Sudar D, Thibault G, Weeder BR, Zheng C, Nan X, Thompson RF, Heiser LM, Spellman PT, Thomas G, Demir E, Chang YH, Coussens LM, Guimaraes AR, Corless C, Goecks J, Bergan R, Mitri Z, Mills GB, Gray JW. Johnson BE, et al. Among authors: spellman pt. Cell Rep Med. 2022 Feb 15;3(2):100525. doi: 10.1016/j.xcrm.2022.100525. eCollection 2022 Feb 15. Cell Rep Med. 2022. PMID: 35243422 Free PMC article.
178 results