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Medroxyprogesterone acetate, unlike norethisterone, increases HIV-1 replication in human peripheral blood mononuclear cells and an indicator cell line, via mechanisms involving the glucocorticoid receptor, increased CD4/CD8 ratios and CCR5 levels.
Maritz MF, Ray RM, Bick AJ, Tomasicchio M, Woodland JG, Govender Y, Avenant C, Hapgood JP. Maritz MF, et al. Among authors: govender y. PLoS One. 2018 Apr 26;13(4):e0196043. doi: 10.1371/journal.pone.0196043. eCollection 2018. PLoS One. 2018. PMID: 29698514 Free PMC article.
15 results