Macedo B - Search Results

1

Liquid-liquid phase separation and fibrillation of the prion protein modulated by a high-affinity DNA aptamer.

Matos CO, Passos YM, do Amaral MJ, Macedo B, Tempone MH, Bezerra OCL, Moraes MO, Almeida MS, Weber G, Missailidis S, Silva JL, Uversky VN, Pinheiro AS, Cordeiro Y. Matos CO, et al. Among authors: macedo b. FASEB J. 2020 Jan;34(1):365-385. doi: 10.1096/fj.201901897R. Epub 2019 Nov 22. FASEB J. 2020. PMID: 31914616

2

Unraveling Prion Protein Interactions with Aptamers and Other PrP-Binding Nucleic Acids.

Macedo B, Cordeiro Y. Macedo B, et al. Int J Mol Sci. 2017 May 17;18(5):1023. doi: 10.3390/ijms18051023. Int J Mol Sci. 2017. PMID: 28513534 Free PMC article. Review.

3

Prion protein complexed to a DNA aptamer induce behavioral and synapse dysfunction in mice.

P B Gomes M, de Lima EV, G Q Barros-Aragão F, Passos YM, Lemos FS, Zamberlan DC, Ribeiro G, Macedo B, C Ferreira N, Silva JL, Figueiredo CP, Clarke JR, Cordeiro Y. P B Gomes M, et al. Among authors: macedo b. Behav Brain Res. 2022 Feb 15;419:113680. doi: 10.1016/j.bbr.2021.113680. Epub 2021 Nov 22. Behav Brain Res. 2022. PMID: 34822947

4

Nonspecific prion protein-nucleic acid interactions lead to different aggregates and cytotoxic species.

Macedo B, Millen TA, Braga CA, Gomes MP, Ferreira PS, Kraineva J, Winter R, Silva JL, Cordeiro Y. Macedo B, et al. Biochemistry. 2012 Jul 10;51(27):5402-13. doi: 10.1021/bi300440e. Epub 2012 Jun 25. Biochemistry. 2012. PMID: 22691027

5

Mammalian prion amyloid formation in bacteria.

Macedo B, Cordeiro Y, Ventura S. Macedo B, et al. Prion. 2016 Mar 3;10(2):112-8. doi: 10.1080/19336896.2016.1141859. Prion. 2016. PMID: 26910379 Free PMC article.

6

Synthesis and anti-prion activity evaluation of aminoquinoline analogues.

Macedo B, Kaschula CH, Hunter R, Chaves JA, van der Merwe JD, Silva JL, Egan TJ, Cordeiro Y. Macedo B, et al. Eur J Med Chem. 2010 Nov;45(11):5468-73. doi: 10.1016/j.ejmech.2010.07.054. Epub 2010 Aug 6. Eur J Med Chem. 2010. PMID: 20797807

7

Mammalian prion protein (PrP) forms conformationally different amyloid intracellular aggregates in bacteria.

Macedo B, Sant'Anna R, Navarro S, Cordeiro Y, Ventura S. Macedo B, et al. Microb Cell Fact. 2015 Nov 4;14:174. doi: 10.1186/s12934-015-0361-y. Microb Cell Fact. 2015. PMID: 26536866 Free PMC article.

8

Pathological implications of nucleic acid interactions with proteins associated with neurodegenerative diseases.

Cordeiro Y, Macedo B, Silva JL, Gomes MPB. Cordeiro Y, et al. Among authors: macedo b. Biophys Rev. 2014 Mar;6(1):97-110. doi: 10.1007/s12551-013-0132-0. Epub 2014 Jan 9. Biophys Rev. 2014. PMID: 28509960 Free PMC article. Review.

9

Biophysical and morphological studies on the dual interaction of non-octarepeat prion protein peptides with copper and nucleic acids.

Chaves JA, Sanchez-López C, Gomes MP, Sisnande T, Macedo B, de Oliveira VE, Braga CA, Rangel LP, Silva JL, Quintanar L, Cordeiro Y. Chaves JA, et al. Among authors: macedo b. J Biol Inorg Chem. 2014 Aug;19(6):839-51. doi: 10.1007/s00775-014-1115-8. Epub 2014 Feb 21. J Biol Inorg Chem. 2014. PMID: 24557708

10

The interplay between a GC-rich oligonucleotide and copper ions on prion protein conformational and phase transitions.

M Passos Y, J do Amaral M, C Ferreira N, Macedo B, Chaves JAP, E de Oliveira V, P B Gomes M, L Silva J, Cordeiro Y. M Passos Y, et al. Among authors: macedo b. Int J Biol Macromol. 2021 Mar 15;173:34-43. doi: 10.1016/j.ijbiomac.2021.01.097. Epub 2021 Jan 18. Int J Biol Macromol. 2021. PMID: 33476618

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