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Antenatal Intracellular Concentrations of Tenofovir Diphosphate and Emtricitabine Triphosphate and Associations Between Tenofovir Diphosphate and Severe Adverse Pregnancy Outcomes: IMPAACT-PROMISE (1077BF) Trial.
Aizire J, Brooks KM, Mirochnick M, Flynn PM, Butler K, Kiser JJ, Siberry GK, Fenton T, Cababasay M, Fowler MG; PROMISE Study Team. Aizire J, et al. Among authors: brooks km. J Acquir Immune Defic Syndr. 2020 Feb 1;83(2):173-180. doi: 10.1097/QAI.0000000000002247. J Acquir Immune Defic Syndr. 2020. PMID: 31929405 Free PMC article. Clinical Trial.
Pharmacokinetics of tenofovir monoester and association with intracellular tenofovir diphosphate following single-dose tenofovir disoproxil fumarate.
Brooks KM, Ibrahim ME, Castillo-Mancilla JR, MaWhinney S, Alexander K, Tilden S, Kerr BJ, Ellison L, McHugh C, Bushman LR, Kiser JJ, Hosek S, Huhn GD, Anderson PL. Brooks KM, et al. J Antimicrob Chemother. 2019 Aug 1;74(8):2352-2359. doi: 10.1093/jac/dkz187. J Antimicrob Chemother. 2019. PMID: 31093649 Free PMC article. Clinical Trial.
Tenofovir alafenamide use in pregnant and lactating women living with HIV.
Eke AC, Brooks KM, Gebreyohannes RD, Sheffield JS, Dooley KE, Mirochnick M. Eke AC, et al. Among authors: brooks km. Expert Opin Drug Metab Toxicol. 2020 Apr;16(4):333-342. doi: 10.1080/17425255.2020.1738384. Epub 2020 Mar 17. Expert Opin Drug Metab Toxicol. 2020. PMID: 32125906 Free PMC article. Review.
Intracellular Tenofovir-Diphosphate and Emtricitabine-Triphosphate in Dried Blood Spots Following Tenofovir Alafenamide: The TAF-DBS Study.
Yager J, Castillo-Mancilla J, Ibrahim ME, Brooks KM, McHugh C, Morrow M, McCallister S, Bushman LR, MaWhinney S, Kiser JJ, Anderson PL. Yager J, et al. Among authors: brooks km. J Acquir Immune Defic Syndr. 2020 Jul 1;84(3):323-330. doi: 10.1097/QAI.0000000000002354. J Acquir Immune Defic Syndr. 2020. PMID: 32539288 Clinical Trial.
Pharmacokinetics and renal safety of tenofovir alafenamide with boosted protease inhibitors and ledipasvir/sofosbuvir.
Brooks KM, Castillo-Mancilla JR, Morrow M, MaWhinney S, Blum J, Wyles DL, Rowan SE, Ibrahim ME, Zheng JH, Johnson B, Gomez J, Choi YJ, Cendali F, Haas H, Roon L, Bushman LR, Anderson PL, Kiser JJ. Brooks KM, et al. J Antimicrob Chemother. 2020 Nov 1;75(11):3303-3310. doi: 10.1093/jac/dkaa299. J Antimicrob Chemother. 2020. PMID: 32766700 Free PMC article.
Optimizing Pharmacology Studies in Pregnant and Lactating Women Using Lessons From HIV: A Consensus Statement.
Eke AC, Olagunju A, Momper J, Penazzato M, Abrams EJ, Best BM, Capparelli EV, Bekker A, Belew Y, Kiser JJ, Struble K, Taylor G, Waitt C, Mirochnick M, Cressey TR, Colbers A; participants of the WHO-IMPAACT workshop on “Approaches to Optimize and Accelerate Pharmacokinetic Studies in Pregnant and Lactating Women”. Eke AC, et al. Clin Pharmacol Ther. 2021 Jul;110(1):36-48. doi: 10.1002/cpt.2048. Epub 2020 Oct 15. Clin Pharmacol Ther. 2021. PMID: 32930408 Free PMC article.
Individualized Adherence Benchmarks for HIV Pre-Exposure Prophylaxis.
Ibrahim ME, Castillo-Mancilla JR, Yager J, Brooks KM, Bushman L, Saba L, Kiser JJ, MaWhinney S, Anderson PL. Ibrahim ME, et al. Among authors: brooks km. AIDS Res Hum Retroviruses. 2021 Jun;37(6):421-428. doi: 10.1089/AID.2020.0108. Epub 2020 Dec 10. AIDS Res Hum Retroviruses. 2021. PMID: 33191774 Free PMC article. Clinical Trial.
Pharmacokinetics of tenofovir alafenamide with and without cobicistat in pregnant and postpartum women living with HIV.
Brooks KM, Momper JD, Pinilla M, Stek AM, Barr E, Weinberg A, Deville JG, Febo IL, Cielo M, George K, Denson K, Rungruengthanakit K, Shapiro DE, Smith E, Chakhtoura N, Rooney JF, Haubrich R, Espina R, Capparelli EV, Mirochnick M, Best BM; IMPAACT P1026s Protocol Team. Brooks KM, et al. AIDS. 2021 Mar 1;35(3):407-417. doi: 10.1097/QAD.0000000000002767. AIDS. 2021. PMID: 33252495 Free PMC article.
97 results