Yan Y - Search Results

1

LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate.

Gao Y, Yan Y, Tripathi S, Pentinmikko N, Amaral A, Päivinen P, Domènech-Moreno E, Andersson S, Wong IPL, Clevers H, Katajisto P, Mäkelä TP. Gao Y, et al. Among authors: yan y. Gastroenterology. 2020 Apr;158(5):1389-1401.e10. doi: 10.1053/j.gastro.2019.12.033. Epub 2020 Jan 11. Gastroenterology. 2020. PMID: 31930988

2

Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway.

Ollila S, Domènech-Moreno E, Laajanen K, Wong IP, Tripathi S, Pentinmikko N, Gao Y, Yan Y, Niemelä EH, Wang TC, Viollet B, Leone G, Katajisto P, Vaahtomeri K, Mäkelä TP. Ollila S, et al. Among authors: yan y. J Clin Invest. 2018 Jan 2;128(1):402-414. doi: 10.1172/JCI93597. Epub 2017 Dec 4. J Clin Invest. 2018. PMID: 29202476 Free PMC article.

3

Inactivation of AMPK Leads to Attenuation of Antigen Presentation and Immune Evasion in Lung Adenocarcinoma.

Gao Y, Päivinen P, Tripathi S, Domènech-Moreno E, Wong IPL, Vaahtomeri K, Nagaraj AS, Talwelkar SS, Foretz M, Verschuren EW, Viollet B, Yan Y, Mäkelä TP. Gao Y, et al. Among authors: yan y. Clin Cancer Res. 2022 Jan 1;28(1):227-237. doi: 10.1158/1078-0432.CCR-21-2049. Epub 2021 Oct 19. Clin Cancer Res. 2022. PMID: 34667030 Free article.

4

SUMOylation of AMPKα1 by PIAS4 specifically regulates mTORC1 signalling.

Yan Y, Ollila S, Wong IPL, Vallenius T, Palvimo JJ, Vaahtomeri K, Mäkelä TP. Yan Y, et al. Nat Commun. 2015 Nov 30;6:8979. doi: 10.1038/ncomms9979. Nat Commun. 2015. PMID: 26616021 Free PMC article.

5

AMPK negatively regulates tensin-dependent integrin activity.

Georgiadou M, Lilja J, Jacquemet G, Guzmán C, Rafaeva M, Alibert C, Yan Y, Sahgal P, Lerche M, Manneville JB, Mäkelä TP, Ivaska J. Georgiadou M, et al. Among authors: yan y. J Cell Biol. 2017 Apr 3;216(4):1107-1121. doi: 10.1083/jcb.201609066. Epub 2017 Mar 13. J Cell Biol. 2017. PMID: 28289092 Free PMC article.

6

Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis.

Nieminen AI, Eskelinen VM, Haikala HM, Tervonen TA, Yan Y, Partanen JI, Klefström J. Nieminen AI, et al. Among authors: yan y. Proc Natl Acad Sci U S A. 2013 May 14;110(20):E1839-48. doi: 10.1073/pnas.1208530110. Epub 2013 Apr 15. Proc Natl Acad Sci U S A. 2013. PMID: 23589839 Free PMC article.

7

Phosphatase PHLPP2 regulates the cellular response to metabolic stress through AMPK.

Yan Y, Krecke KN, Bapat AS, Yang T, Lopresti MW, Mashek DG, Kelekar A. Yan Y, et al. Cell Death Dis. 2021 Oct 4;12(10):904. doi: 10.1038/s41419-021-04196-4. Cell Death Dis. 2021. PMID: 34608126 Free PMC article.

8

Transcription factor C/EBP-β induces tumor-suppressor phosphatase PHLPP2 through repression of the miR-17-92 cluster in differentiating AML cells.

Yan Y, Hanse EA, Stedman K, Benson JM, Lowman XH, Subramanian S, Kelekar A. Yan Y, et al. Cell Death Differ. 2016 Jul;23(7):1232-42. doi: 10.1038/cdd.2016.1. Epub 2016 Feb 12. Cell Death Differ. 2016. PMID: 26868909 Free PMC article.

9

Collaborative control technology and application of support and modification for soft-rock roadway in a kilometer-deep coal mine.

Wang E, Yin S, Chen X, Gao Z, Sun A, Yan Y. Wang E, et al. Among authors: yan y. Sci Rep. 2025 Jan 15;15(1):1979. doi: 10.1038/s41598-025-86269-4. Sci Rep. 2025. PMID: 39809979

10

Activation of three targets by a TAL effector confers susceptibility to bacterial blight of cotton.

Mormile BW, Yan Y, Bauer T, Wang L, Rivero RC, Carpenter SCD, Danmaigona Clement C, Cox KL, Zhang L, Ma X, Wheeler TA, Dever JK, He P, Bogdanove AJ, Shan L. Mormile BW, et al. Among authors: yan y. Nat Commun. 2025 Jan 14;16(1):644. doi: 10.1038/s41467-025-55926-7. Nat Commun. 2025. PMID: 39809734

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