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Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3.
de Las Rivas M, Paul Daniel EJ, Narimatsu Y, Compañón I, Kato K, Hermosilla P, Thureau A, Ceballos-Laita L, Coelho H, Bernadó P, Marcelo F, Hansen L, Maeda R, Lostao A, Corzana F, Clausen H, Gerken TA, Hurtado-Guerrero R. de Las Rivas M, et al. Nat Chem Biol. 2020 Mar;16(3):351-360. doi: 10.1038/s41589-019-0444-x. Epub 2020 Jan 13. Nat Chem Biol. 2020. PMID: 31932717 Free PMC article.
Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality.
Albert MC, Uranga-Murillo I, Arias M, De Miguel D, Peña N, Montinaro A, Varanda AB, Theobald SJ, Areso I, Saggau J, Koch M, Liccardi G, Peltzer N, Rybniker J, Hurtado-Guerrero R, Merino P, Monzón M, Badiola JJ, Reindl-Schwaighofer R, Sanz-Pamplona R, Cebollada-Solanas A, Megyesfalvi Z, Dome B, Secrier M, Hartmann B, Bergmann M, Pardo J, Walczak H. Albert MC, et al. Among authors: hurtado guerrero r. Cell Death Differ. 2024 May;31(5):544-557. doi: 10.1038/s41418-024-01278-6. Epub 2024 Mar 21. Cell Death Differ. 2024. PMID: 38514848 Free PMC article.
Substrate-guided front-face reaction revealed by combined structural snapshots and metadynamics for the polypeptide N-acetylgalactosaminyltransferase 2.
Lira-Navarrete E, Iglesias-Fernández J, Zandberg WF, Compañón I, Kong Y, Corzana F, Pinto BM, Clausen H, Peregrina JM, Vocadlo DJ, Rovira C, Hurtado-Guerrero R. Lira-Navarrete E, et al. Angew Chem Int Ed Engl. 2014 Jul 28;53(31):8206-10. doi: 10.1002/anie.201402781. Epub 2014 Jun 20. Angew Chem Int Ed Engl. 2014. PMID: 24954443
Serine versus threonine glycosylation with α-O-GalNAc: unexpected selectivity in their molecular recognition with lectins.
Madariaga D, Martínez-Sáez N, Somovilla VJ, García-García L, Berbis MÁ, Valero-Gónzalez J, Martín-Santamaría S, Hurtado-Guerrero R, Asensio JL, Jiménez-Barbero J, Avenoza A, Busto JH, Corzana F, Peregrina JM. Madariaga D, et al. Chemistry. 2014 Sep 22;20(39):12616-27. doi: 10.1002/chem.201403700. Epub 2014 Aug 8. Chemistry. 2014. PMID: 25111627
Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody.
Martínez-Sáez N, Castro-López J, Valero-González J, Madariaga D, Compañón I, Somovilla VJ, Salvadó M, Asensio JL, Jiménez-Barbero J, Avenoza A, Busto JH, Bernardes GJ, Peregrina JM, Hurtado-Guerrero R, Corzana F. Martínez-Sáez N, et al. Angew Chem Int Ed Engl. 2015 Aug 17;54(34):9830-4. doi: 10.1002/anie.201502813. Epub 2015 Jun 26. Angew Chem Int Ed Engl. 2015. PMID: 26118689 Free PMC article.
A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2.
Valero-González J, Leonhard-Melief C, Lira-Navarrete E, Jiménez-Osés G, Hernández-Ruiz C, Pallarés MC, Yruela I, Vasudevan D, Lostao A, Corzana F, Takeuchi H, Haltiwanger RS, Hurtado-Guerrero R. Valero-González J, et al. Nat Chem Biol. 2016 Apr;12(4):240-6. doi: 10.1038/nchembio.2019. Epub 2016 Feb 8. Nat Chem Biol. 2016. PMID: 26854667 Free PMC article.
117 results