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196 results

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Peptide-TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens.
Lynn GM, Sedlik C, Baharom F, Zhu Y, Ramirez-Valdez RA, Coble VL, Tobin K, Nichols SR, Itzkowitz Y, Zaidi N, Gammon JM, Blobel NJ, Denizeau J, de la Rochere P, Francica BJ, Decker B, Maciejewski M, Cheung J, Yamane H, Smelkinson MG, Francica JR, Laga R, Bernstock JD, Seymour LW, Drake CG, Jewell CM, Lantz O, Piaggio E, Ishizuka AS, Seder RA. Lynn GM, et al. Among authors: bernstock jd. Nat Biotechnol. 2020 Mar;38(3):320-332. doi: 10.1038/s41587-019-0390-x. Epub 2020 Jan 13. Nat Biotechnol. 2020. PMID: 31932728 Free PMC article.
Oncolytic herpes simplex virus immunotherapy for brain tumors: current pitfalls and emerging strategies to overcome therapeutic resistance.
Totsch SK, Schlappi C, Kang KD, Ishizuka AS, Lynn GM, Fox B, Beierle EA, Whitley RJ, Markert JM, Gillespie GY, Bernstock JD, Friedman GK. Totsch SK, et al. Among authors: bernstock jd. Oncogene. 2019 Aug;38(34):6159-6171. doi: 10.1038/s41388-019-0870-y. Epub 2019 Jul 9. Oncogene. 2019. PMID: 31289361 Free PMC article. Review.
Combination Immunotherapy with Vaccine and Oncolytic HSV Virotherapy Is Time Dependent.
Totsch SK, Ishizuka AS, Kang KD, Gary SE, Rocco A, Fan AE, Zhou L, Valdes PA, Lee S, Li J, Peruzzotti-Jametti L, Blitz S, Garliss CM, Johnston JM, Markert JM, Lynn GM, Bernstock JD, Friedman GK. Totsch SK, et al. Among authors: bernstock jd. Mol Cancer Ther. 2024 Sep 4;23(9):1273-1281. doi: 10.1158/1535-7163.MCT-23-0873. Mol Cancer Ther. 2024. PMID: 38710101
Clinical trial links oncolytic immunoactivation to survival in glioblastoma.
Ling AL, Solomon IH, Landivar AM, Nakashima H, Woods JK, Santos A, Masud N, Fell G, Mo X, Yilmaz AS, Grant J, Zhang A, Bernstock JD, Torio E, Ito H, Liu J, Shono N, Nowicki MO, Triggs D, Halloran P, Piranlioglu R, Soni H, Stopa B, Bi WL, Peruzzi P, Chen E, Malinowski SW, Prabhu MC, Zeng Y, Carlisle A, Rodig SJ, Wen PY, Lee EQ, Nayak L, Chukwueke U, Gonzalez Castro LN, Dumont SD, Batchelor T, Kittelberger K, Tikhonova E, Miheecheva N, Tabakov D, Shin N, Gorbacheva A, Shumskiy A, Frenkel F, Aguilar-Cordova E, Aguilar LK, Krisky D, Wechuck J, Manzanera A, Matheny C, Tak PP, Barone F, Kovarsky D, Tirosh I, Suvà ML, Wucherpfennig KW, Ligon K, Reardon DA, Chiocca EA. Ling AL, et al. Among authors: bernstock jd. Nature. 2023 Nov;623(7985):157-166. doi: 10.1038/s41586-023-06623-2. Epub 2023 Oct 18. Nature. 2023. PMID: 37853118 Free PMC article. Clinical Trial.
Next-generation CAR T cell therapies for glioblastoma.
Bernstock JD, Gerstl JVE, Valdés PA, Friedman GK, Chiocca E. Bernstock JD, et al. Sci Transl Med. 2024 Aug 28;16(762):eadp2660. doi: 10.1126/scitranslmed.adp2660. Epub 2024 Aug 28. Sci Transl Med. 2024. PMID: 39196960 Review.
Drugging SUMOylation for neuroprotection and oncotherapy.
Bernstock JD, Ye DG, Lee YJ, Gessler F, Friedman GK, Zheng W, Hallenbeck JM. Bernstock JD, et al. Neural Regen Res. 2018 Mar;13(3):415-416. doi: 10.4103/1673-5374.228718. Neural Regen Res. 2018. PMID: 29623920 Free PMC article. No abstract available.
Enhanced Sensitivity of Patient-Derived Pediatric High-Grade Brain Tumor Xenografts to Oncolytic HSV-1 Virotherapy Correlates with Nectin-1 Expression.
Friedman GK, Bernstock JD, Chen D, Nan L, Moore BP, Kelly VM, Youngblood SL, Langford CP, Han X, Ring EK, Beierle EA, Gillespie GY, Markert JM. Friedman GK, et al. Among authors: bernstock jd. Sci Rep. 2018 Sep 17;8(1):13930. doi: 10.1038/s41598-018-32353-x. Sci Rep. 2018. PMID: 30224769 Free PMC article.
196 results