Empting M - Search Results

1

Discovery of Novel Latency-Associated Nuclear Antigen Inhibitors as Antiviral Agents Against Kaposi's Sarcoma-Associated Herpesvirus.

Kirsch P, Jakob V, Elgaher WAM, Walt C, Oberhausen K, Schulz TF, Empting M. Kirsch P, et al. Among authors: empting m. ACS Chem Biol. 2020 Feb 21;15(2):388-395. doi: 10.1021/acschembio.9b00845. Epub 2020 Jan 24. ACS Chem Biol. 2020. PMID: 31944659

2

Biochemical and biophysical analysis of a chiral PqsD inhibitor revealing tight-binding behavior and enantiomers with contrary thermodynamic signatures.

Storz MP, Brengel C, Weidel E, Hoffmann M, Hollemeyer K, Steinbach A, Müller R, Empting M, Hartmann RW. Storz MP, et al. Among authors: empting m. ACS Chem Biol. 2013 Dec 20;8(12):2794-801. doi: 10.1021/cb400530d. Epub 2013 Oct 25. ACS Chem Biol. 2013. PMID: 24099650

3

Composing compound libraries for hit discovery--rationality-driven preselection or random choice by structural diversity?

Weidel E, Negri M, Empting M, Hinsberger S, Hartmann RW. Weidel E, et al. Among authors: empting m. Future Med Chem. 2014;6(18):2057-72. doi: 10.4155/fmc.14.142. Future Med Chem. 2014. PMID: 25531968

4

Application of Dual Inhibition Concept within Looped Autoregulatory Systems toward Antivirulence Agents against Pseudomonas aeruginosa Infections.

Thomann A, de Mello Martins AG, Brengel C, Empting M, Hartmann RW. Thomann A, et al. Among authors: empting m. ACS Chem Biol. 2016 May 20;11(5):1279-86. doi: 10.1021/acschembio.6b00117. Epub 2016 Mar 1. ACS Chem Biol. 2016. PMID: 26882081

5

Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds.

Zender M, Witzgall F, Drees SL, Weidel E, Maurer CK, Fetzner S, Blankenfeldt W, Empting M, Hartmann RW. Zender M, et al. Among authors: empting m. ACS Chem Biol. 2016 Jun 17;11(6):1755-63. doi: 10.1021/acschembio.6b00156. Epub 2016 Apr 28. ACS Chem Biol. 2016. PMID: 27082157

6

Discovery of the first small-molecule CsrA-RNA interaction inhibitors using biophysical screening technologies.

Maurer CK, Fruth M, Empting M, Avrutina O, Hoßmann J, Nadmid S, Gorges J, Herrmann J, Kazmaier U, Dersch P, Müller R, Hartmann RW. Maurer CK, et al. Among authors: empting m. Future Med Chem. 2016 Jun;8(9):931-47. doi: 10.4155/fmc-2016-0033. Epub 2016 Jun 2. Future Med Chem. 2016. PMID: 27253623

7

Biophysical Screening of a Focused Library for the Discovery of CYP121 Inhibitors as Novel Antimycobacterials.

Brengel C, Thomann A, Schifrin A, Allegretta G, Kamal AAM, Haupenthal J, Schnorr I, Cho SH, Franzblau SG, Empting M, Eberhard J, Hartmann RW. Brengel C, et al. Among authors: empting m. ChemMedChem. 2017 Oct 9;12(19):1616-1626. doi: 10.1002/cmdc.201700363. Epub 2017 Sep 26. ChemMedChem. 2017. PMID: 28815923 Free article.

8

In Vitro Model of the Gram-Negative Bacterial Cell Envelope for Investigation of Anti-Infective Permeation Kinetics.

Graef F, Richter R, Fetz V, Murgia X, De Rossi C, Schneider-Daum N, Allegretta G, Elgaher W, Haupenthal J, Empting M, Beckmann F, Brönstrup M, Hartmann R, Gordon S, Lehr CM. Graef F, et al. Among authors: empting m. ACS Infect Dis. 2018 Aug 10;4(8):1188-1196. doi: 10.1021/acsinfecdis.7b00165. Epub 2018 May 24. ACS Infect Dis. 2018. PMID: 29750862

9

Tackling Pseudomonas aeruginosa Virulence by a Hydroxamic Acid-Based LasB Inhibitor.

Kany AM, Sikandar A, Yahiaoui S, Haupenthal J, Walter I, Empting M, Köhnke J, Hartmann RW. Kany AM, et al. Among authors: empting m. ACS Chem Biol. 2018 Sep 21;13(9):2449-2455. doi: 10.1021/acschembio.8b00257. Epub 2018 Aug 24. ACS Chem Biol. 2018. PMID: 30088919 Free article.

10

Fragment-Based Discovery of a Qualified Hit Targeting the Latency-Associated Nuclear Antigen of the Oncogenic Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8.

Kirsch P, Jakob V, Oberhausen K, Stein SC, Cucarro I, Schulz TF, Empting M. Kirsch P, et al. Among authors: empting m. J Med Chem. 2019 Apr 25;62(8):3924-3939. doi: 10.1021/acs.jmedchem.8b01827. Epub 2019 Apr 12. J Med Chem. 2019. PMID: 30888817

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