Kang BH - Search Results

1

Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1.

Park HK, Yoon NG, Lee JE, Hu S, Yoon S, Kim SY, Hong JH, Nam D, Chae YC, Park JB, Kang BH. Park HK, et al. Among authors: kang bh. Exp Mol Med. 2020 Jan;52(1):79-91. doi: 10.1038/s12276-019-0360-x. Epub 2020 Jan 20. Exp Mol Med. 2020. PMID: 31956271 Free PMC article.

2

TRAP1 regulation of mitochondrial life or death decision in cancer cells and mitochondria-targeted TRAP1 inhibitors.

Kang BH. Kang BH. BMB Rep. 2012 Jan;45(1):1-6. doi: 10.5483/bmbrep.2012.45.1.1. BMB Rep. 2012. PMID: 22281005 Free article. Review.

3

Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from mitochondria to the ER in cancer cells.

Park HK, Lee JE, Lim J, Kang BH. Park HK, et al. Among authors: kang bh. Mol Cancer. 2014 Jun 12;13:148. doi: 10.1186/1476-4598-13-148. Mol Cancer. 2014. PMID: 24924916 Free PMC article.

4

Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim.

Park HK, Lee JE, Lim J, Jo DE, Park SA, Suh PG, Kang BH. Park HK, et al. Among authors: kang bh. BMC Cancer. 2014 Jun 13;14:431. doi: 10.1186/1471-2407-14-431. BMC Cancer. 2014. PMID: 24927938 Free PMC article.

5

Crystallization and preliminary X-ray diffraction analysis of Trap1 complexed with Hsp90 inhibitors.

Jeong H, Kang BH, Lee C. Jeong H, et al. Among authors: kang bh. Acta Crystallogr F Struct Biol Commun. 2014 Dec 1;70(Pt 12):1683-7. doi: 10.1107/S2053230X14024959. Epub 2014 Nov 28. Acta Crystallogr F Struct Biol Commun. 2014. PMID: 25484226 Free PMC article.

6

Development of a mitochondria-targeted Hsp90 inhibitor based on the crystal structures of human TRAP1.

Lee C, Park HK, Jeong H, Lim J, Lee AJ, Cheon KY, Kim CS, Thomas AP, Bae B, Kim ND, Kim SH, Suh PG, Ryu JH, Kang BH. Lee C, et al. Among authors: kang bh. J Am Chem Soc. 2015 Apr 8;137(13):4358-67. doi: 10.1021/ja511893n. Epub 2015 Mar 30. J Am Chem Soc. 2015. PMID: 25785725

7

Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors.

Park HK, Jeong H, Ko E, Lee G, Lee JE, Lee SK, Lee AJ, Im JY, Hu S, Kim SH, Lee JH, Lee C, Kang S, Kang BH. Park HK, et al. Among authors: kang s, kang bh. J Med Chem. 2017 Sep 14;60(17):7569-7578. doi: 10.1021/acs.jmedchem.7b00978. Epub 2017 Aug 30. J Med Chem. 2017. PMID: 28816449

8

TRAP1 Inhibition Increases Glutamine Synthetase Activity in Glutamine Auxotrophic Non-small Cell Lung Cancer Cells.

Vo VTA, Choi JW, Phan ANH, Hua TNM, Kim MK, Kang BH, Jung SH, Yong SJ, Jeong Y. Vo VTA, et al. Among authors: kang bh. Anticancer Res. 2018 Apr;38(4):2187-2193. doi: 10.21873/anticanres.12460. Anticancer Res. 2018. PMID: 29599338

9

Interplay between TRAP1 and Sirtuin-3 Modulates Mitochondrial Respiration and Oxidative Stress to Maintain Stemness of Glioma Stem Cells.

Park HK, Hong JH, Oh YT, Kim SS, Yin J, Lee AJ, Chae YC, Kim JH, Park SH, Park CK, Park MJ, Park JB, Kang BH. Park HK, et al. Among authors: kang bh. Cancer Res. 2019 Apr 1;79(7):1369-1382. doi: 10.1158/0008-5472.CAN-18-2558. Epub 2019 Jan 25. Cancer Res. 2019. PMID: 30683653

10

Mitochondrial heat shock protein-guided photodynamic therapy.

Thomas AP, Lee AJ, Palanikumar L, Jana B, Kim K, Kim S, Ok H, Seol J, Kim D, Kang BH, Ryu JH. Thomas AP, et al. Among authors: kang bh. Chem Commun (Camb). 2019 Oct 17;55(84):12631-12634. doi: 10.1039/c9cc06411g. Chem Commun (Camb). 2019. PMID: 31580341

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