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Variants in NGLY1 lead to intellectual disability, myoclonus epilepsy, sensorimotor axonal polyneuropathy and mitochondrial dysfunction.
Panneman DM, Wortmann SB, Haaxma CA, van Hasselt PM, Wolf NI, Hendriks Y, Küsters B, van Emst-de Vries S, van de Westerlo E, Koopman WJH, Wintjes L, van den Brandt F, de Vries M, Lefeber DJ, Smeitink JAM, Rodenburg RJ. Panneman DM, et al. Among authors: van de westerlo e. Clin Genet. 2020 Apr;97(4):556-566. doi: 10.1111/cge.13706. Epub 2020 Jan 30. Clin Genet. 2020. PMID: 31957011 Free PMC article.
Mitochondria-targeted phenolic antioxidants induce ROS-protective pathways in primary human skin fibroblasts.
Teixeira J, Basit F, Willems PHGM, Wagenaars JA, van de Westerlo E, Amorim R, Cagide F, Benfeito S, Oliveira C, Borges F, Oliveira PJ, Koopman WJH. Teixeira J, et al. Among authors: van de westerlo e. Free Radic Biol Med. 2021 Feb 1;163:314-324. doi: 10.1016/j.freeradbiomed.2020.12.023. Epub 2020 Dec 29. Free Radic Biol Med. 2021. PMID: 33359686
oxLDL-Induced Trained Immunity Is Dependent on Mitochondrial Metabolic Reprogramming.
Groh LA, Ferreira AV, Helder L, van der Heijden CDCC, Novakovic B, van de Westerlo E, Matzaraki V, Moorlag SJCFM, de Bree LC, Koeken VACM, Mourits VP, Keating ST, van Puffelen JH, Hoischen A, Joosten LAB, Netea MG, Koopman WJH, Riksen NP. Groh LA, et al. Among authors: van de westerlo e. Immunometabolism. 2021 Jun 30;3(3):e210025. doi: 10.20900/immunometab20210025. eCollection 2021. Immunometabolism. 2021. PMID: 34267957 Free PMC article.
The decylTPP mitochondria-targeting moiety lowers electron transport chain supercomplex levels in primary human skin fibroblasts.
Bulthuis EP, Einer C, Distelmaier F, Groh L, van Emst-de Vries SE, van de Westerlo E, van de Wal M, Wagenaars J, Rodenburg RJ, Smeitink JAM, Riksen NP, Willems PHGM, Adjobo-Hermans MJW, Zischka H, Koopman WJH. Bulthuis EP, et al. Among authors: van de westerlo e. Free Radic Biol Med. 2022 Aug 1;188:434-446. doi: 10.1016/j.freeradbiomed.2022.06.011. Epub 2022 Jun 17. Free Radic Biol Med. 2022. PMID: 35718301 Free article.
Stress-dependent macromolecular crowding in the mitochondrial matrix.
Bulthuis EP, Dieteren CEJ, Bergmans J, Berkhout J, Wagenaars JA, van de Westerlo EMA, Podhumljak E, Hink MA, Hesp LFB, Rosa HS, Malik AN, Lindert MK, Willems PHGM, Gardeniers HJGE, den Otter WK, Adjobo-Hermans MJW, Koopman WJH. Bulthuis EP, et al. Among authors: van de westerlo ema. EMBO J. 2023 Apr 3;42(7):e108533. doi: 10.15252/embj.2021108533. Epub 2023 Feb 24. EMBO J. 2023. PMID: 36825437 Free PMC article.
Heterogeneity of heparan sulfates in human lung.
Smits NC, Robbesom AA, Versteeg EM, van de Westerlo EM, Dekhuijzen PN, van Kuppevelt TH. Smits NC, et al. Am J Respir Cell Mol Biol. 2004 Feb;30(2):166-73. doi: 10.1165/rcmb.2003-0198OC. Epub 2003 Aug 1. Am J Respir Cell Mol Biol. 2004. PMID: 12896874
38 results