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Choline transport links macrophage phospholipid metabolism and inflammation.
Snider SA, Margison KD, Ghorbani P, LeBlond ND, O'Dwyer C, Nunes JRC, Nguyen T, Xu H, Bennett SAL, Fullerton MD. Snider SA, et al. J Biol Chem. 2018 Jul 20;293(29):11600-11611. doi: 10.1074/jbc.RA118.003180. Epub 2018 Jun 7. J Biol Chem. 2018. PMID: 29880645 Free PMC article.
Inhibition of Adenosine Monophosphate-Activated Protein Kinase-3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Signaling Leads to Hypercholesterolemia and Promotes Hepatic Steatosis and Insulin Resistance.
Loh K, Tam S, Murray-Segal L, Huynh K, Meikle PJ, Scott JW, van Denderen B, Chen Z, Steel R, LeBlond ND, Burkovsky LA, O'Dwyer C, Nunes JRC, Steinberg GR, Fullerton MD, Galic S, Kemp BE. Loh K, et al. Hepatol Commun. 2018 Nov 12;3(1):84-98. doi: 10.1002/hep4.1279. eCollection 2019 Jan. Hepatol Commun. 2018. PMID: 30619997 Free PMC article.
In Vitro Hepatitis C Virus Infection and Hepatic Choline Metabolism.
Gobeil Odai K, O'Dwyer C, Steenbergen R, Shaw TA, Renner TM, Ghorbani P, Rezaaifar M, Han S, Langlois MA, Crawley AM, Russell RS, Pezacki JP, Tyrrell DL, Fullerton MD. Gobeil Odai K, et al. Viruses. 2020 Jan 16;12(1):108. doi: 10.3390/v12010108. Viruses. 2020. PMID: 31963173 Free PMC article.
Adipose Tissue Inflammation Is Directly Linked to Obesity-Induced Insulin Resistance, while Gut Dysbiosis and Mitochondrial Dysfunction Are Not Required.
Petrick HL, Foley KP, Zlitni S, Brunetta HS, Paglialunga S, Miotto PM, Politis-Barber V, O'Dwyer C, Philbrick DJ, Fullerton MD, Schertzer JD, Holloway GP. Petrick HL, et al. Function (Oxf). 2020 Aug 25;1(2):zqaa013. doi: 10.1093/function/zqaa013. eCollection 2020. Function (Oxf). 2020. PMID: 34278304 Free PMC article.
Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity.
Pileggi CA, Blondin DP, Hooks BG, Parmar G, Alecu I, Patten DA, Cuillerier A, O'Dwyer C, Thrush AB, Fullerton MD, Bennett SA, Doucet É, Haman F, Cuperlovic-Culf M, McPherson R, Dent RRM, Harper ME. Pileggi CA, et al. EBioMedicine. 2022 Sep;83:104192. doi: 10.1016/j.ebiom.2022.104192. Epub 2022 Aug 11. EBioMedicine. 2022. PMID: 35965199 Free PMC article.
Hepatocyte-derived DPP4 regulates portal GLP-1 bioactivity, modulates glucose production, and when absent influences NAFLD progression.
Trzaskalski NA, Vulesevic B, Nguyen MA, Jeraj N, Fadzeyeva E, Morrow NM, Locatelli CA, Travis N, Hanson AA, Nunes JR, O'Dwyer C, van der Veen JN, Lorenzen-Schmidt I, Seymour R, Pulente SM, Clément AC, Crawley AM, Jacobs RL, Doyle MA, Cooper CL, Kim KH, Fullerton MD, Mulvihill EE. Trzaskalski NA, et al. JCI Insight. 2023 Jan 24;8(2):e154314. doi: 10.1172/jci.insight.154314. JCI Insight. 2023. PMID: 36472923 Free PMC article.
150 results