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De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Kessler MD, Loesch DP, Perry JA, Heard-Costa NL, Taliun D, Cade BE, Wang H, Daya M, Ziniti J, Datta S, Celedón JC, Soto-Quiros ME, Avila L, Weiss ST, Barnes K, Redline SS, Vasan RS, Johnson AD, Mathias RA, Hernandez R, Wilson JG, Nickerson DA, Abecasis G, Browning SR, Zöllner S, O'Connell JR, Mitchell BD; National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Population Genetics Working Group; O'Connor TD. Kessler MD, et al. Among authors: browning sr. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2560-2569. doi: 10.1073/pnas.1902766117. Epub 2020 Jan 21. Proc Natl Acad Sci U S A. 2020. PMID: 31964835 Free PMC article.
A fast, powerful method for detecting identity by descent.
Browning BL, Browning SR. Browning BL, et al. Among authors: browning sr. Am J Hum Genet. 2011 Feb 11;88(2):173-82. doi: 10.1016/j.ajhg.2011.01.010. Am J Hum Genet. 2011. PMID: 21310274 Free PMC article.
Population structure can inflate SNP-based heritability estimates.
Browning SR, Browning BL. Browning SR, et al. Among authors: browning bl. Am J Hum Genet. 2011 Jul 15;89(1):191-3; author reply 193-5. doi: 10.1016/j.ajhg.2011.05.025. Am J Hum Genet. 2011. PMID: 21763486 Free PMC article. No abstract available.
131 results