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Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Hepatocellular Carcinomas Following Chronic Liver Injury.
Lin YH, Zhang S, Zhu M, Lu T, Chen K, Wen Z, Wang S, Xiao G, Luo D, Jia Y, Li L, MacConmara M, Hoshida Y, Singal AG, Yopp A, Wang T, Zhu H. Lin YH, et al. Among authors: jia y. Gastroenterology. 2020 May;158(6):1698-1712.e14. doi: 10.1053/j.gastro.2020.01.026. Epub 2020 Jan 20. Gastroenterology. 2020. PMID: 31972235 Free PMC article.
Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer.
Sun X, Wang SC, Wei Y, Luo X, Jia Y, Li L, Gopal P, Zhu M, Nassour I, Chuang JC, Maples T, Celen C, Nguyen LH, Wu L, Fu S, Li W, Hui L, Tian F, Ji Y, Zhang S, Sorouri M, Hwang TH, Letzig L, James L, Wang Z, Yopp AC, Singal AG, Zhu H. Sun X, et al. Among authors: jia y. Cancer Cell. 2017 Nov 13;32(5):574-589.e6. doi: 10.1016/j.ccell.2017.10.007. Cancer Cell. 2017. PMID: 29136504 Free PMC article.
Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer.
Sun X, Wang SC, Wei Y, Luo X, Jia Y, Li L, Gopal P, Zhu M, Nassour I, Chuang JC, Maples T, Celen C, Nguyen LH, Wu L, Fu S, Li W, Hui L, Tian F, Ji Y, Zhang S, Sorouri M, Hwang TH, Letzig L, James L, Wang Z, Yopp AC, Singal AG, Zhu H. Sun X, et al. Among authors: jia y. Cancer Cell. 2018 Jan 8;33(1):151-152. doi: 10.1016/j.ccell.2017.12.011. Cancer Cell. 2018. PMID: 29316428 Free PMC article. No abstract available.
Liver homeostasis is maintained by midlobular zone 2 hepatocytes.
Wei Y, Wang YG, Jia Y, Li L, Yoon J, Zhang S, Wang Z, Zhang Y, Zhu M, Sharma T, Lin YH, Hsieh MH, Albrecht JH, Le PT, Rosen CJ, Wang T, Zhu H. Wei Y, et al. Among authors: jia y. Science. 2021 Feb 26;371(6532):eabb1625. doi: 10.1126/science.abb1625. Science. 2021. PMID: 33632817 Free PMC article.
Arid1a loss potentiates pancreatic β-cell regeneration through activation of EGF signaling.
Celen C, Chuang JC, Shen S, Li L, Maggiore G, Jia Y, Luo X, Moore A, Wang Y, Otto JE, Collings CK, Wang Z, Sun X, Nassour I, Park J, Ghaben A, Wang T, Wang SC, Scherer PE, Kadoch C, Zhu H. Celen C, et al. Among authors: jia y. Cell Rep. 2022 Nov 1;41(5):111581. doi: 10.1016/j.celrep.2022.111581. Cell Rep. 2022. PMID: 36323264 Free article.
Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease.
Wang Z, Zhu S, Jia Y, Wang Y, Kubota N, Fujiwara N, Gordillo R, Lewis C, Zhu M, Sharma T, Li L, Zeng Q, Lin YH, Hsieh MH, Gopal P, Wang T, Hoare M, Campbell P, Hoshida Y, Zhu H. Wang Z, et al. Among authors: jia y. bioRxiv [Preprint]. 2023 Mar 21:2023.03.20.533505. doi: 10.1101/2023.03.20.533505. bioRxiv. 2023. Update in: Cell. 2023 Apr 27;186(9):1968-1984.e20. doi: 10.1016/j.cell.2023.03.014 PMID: 36993727 Free PMC article. Updated. Preprint.
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