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Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1.
Arsiwala T, Pahla J, van Tits LJ, Bisceglie L, Gaul DS, Costantino S, Miranda MX, Nussbaum K, Stivala S, Blyszczuk P, Weber J, Tailleux A, Stein S, Paneni F, Beer JH, Greter M, Becher B, Mostoslavsky R, Eriksson U, Staels B, Auwerx J, Hottiger MO, Lüscher TF, Matter CM. Arsiwala T, et al. J Mol Cell Cardiol. 2020 Feb;139:24-32. doi: 10.1016/j.yjmcc.2020.01.002. Epub 2020 Jan 21. J Mol Cell Cardiol. 2020. PMID: 31972266
The Sirt1 activator SRT3025 provides atheroprotection in Apoe-/- mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression.
Miranda MX, van Tits LJ, Lohmann C, Arsiwala T, Winnik S, Tailleux A, Stein S, Gomes AP, Suri V, Ellis JL, Lutz TA, Hottiger MO, Sinclair DA, Auwerx J, Schoonjans K, Staels B, Lüscher TF, Matter CM. Miranda MX, et al. Among authors: arsiwala t. Eur Heart J. 2015 Jan 1;36(1):51-9. doi: 10.1093/eurheartj/ehu095. Epub 2014 Mar 6. Eur Heart J. 2015. PMID: 24603306 Free PMC article.
Focused Ultrasound Neuromodulation: Exploring a Novel Treatment for Severe Opioid Use Disorder.
Rezai A, Thompson-Lake DGY, D'Haese PF, Meyer N, Ranjan M, Farmer D, Finomore V, Marton JL, Hodder S, Carpenter J, Bhagwat A, Berry J, Tirumalai P, Adams G, Arsiwala T, Blanke O, Mahoney JJ. Rezai A, et al. Among authors: arsiwala t. Biol Psychiatry. 2025 Jan 9:S0006-3223(25)00023-X. doi: 10.1016/j.biopsych.2025.01.001. Online ahead of print. Biol Psychiatry. 2025. PMID: 39798597
Targeting drug resistance in glioblastoma (Review).
Sherman JH, Bobak A, Arsiwala T, Lockman P, Aulakh S. Sherman JH, et al. Among authors: arsiwala t. Int J Oncol. 2024 Aug;65(2):80. doi: 10.3892/ijo.2024.5668. Epub 2024 Jul 12. Int J Oncol. 2024. PMID: 38994761 Free PMC article. Review.
Ultrasound Blood-Brain Barrier Opening and Aducanumab in Alzheimer's Disease.
Rezai AR, D'Haese PF, Finomore V, Carpenter J, Ranjan M, Wilhelmsen K, Mehta RI, Wang P, Najib U, Vieira Ligo Teixeira C, Arsiwala T, Tarabishy A, Tirumalai P, Claassen DO, Hodder S, Haut MW. Rezai AR, et al. Among authors: arsiwala t. N Engl J Med. 2024 Jan 4;390(1):55-62. doi: 10.1056/NEJMoa2308719. N Engl J Med. 2024. PMID: 38169490
Blood-tumor barrier opening by MRI-guided transcranial focused ultrasound in a preclinical breast cancer brain metastasis model improves efficacy of combinatorial chemotherapy.
Arsiwala TA, Blethen KE, Wolford CP, Panchal DM, Sprowls SA, Fladeland RA, Kielkowski BN, Pritt TA, Wang P, Wilson O, Carpenter JS, Finomore V, Rezai A, Lockman PR. Arsiwala TA, et al. Front Oncol. 2023 Feb 10;13:1104594. doi: 10.3389/fonc.2023.1104594. eCollection 2023. Front Oncol. 2023. PMID: 36845739 Free PMC article.
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