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810 results

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Page 1
Glutamatergic abnormalities in schizophrenia: a review of proton MRS findings.
Poels EM, Kegeles LS, Kantrowitz JT, Javitt DC, Lieberman JA, Abi-Dargham A, Girgis RR. Poels EM, et al. Among authors: lieberman ja. Schizophr Res. 2014 Feb;152(2-3):325-32. doi: 10.1016/j.schres.2013.12.013. Epub 2014 Jan 11. Schizophr Res. 2014. PMID: 24418122 Free PMC article. Review.
A Phase II study of a histamine H₃ receptor antagonist GSK239512 for cognitive impairment in stable schizophrenia subjects on antipsychotic therapy.
Jarskog LF, Lowy MT, Grove RA, Keefe RS, Horrigan JP, Ball MP, Breier A, Buchanan RW, Carter CS, Csernansky JG, Goff DC, Green MF, Kantrowitz JT, Keshavan MS, Laurelle M, Lieberman JA, Marder SR, Maruff P, McMahon RP, Seidman LJ, Peykamian MA. Jarskog LF, et al. Among authors: lieberman ja. Schizophr Res. 2015 May;164(1-3):136-42. doi: 10.1016/j.schres.2015.01.041. Epub 2015 Feb 24. Schizophr Res. 2015. PMID: 25728831 Clinical Trial.
A Multicenter, Rater-Blinded, Randomized Controlled Study of Auditory Processing-Focused Cognitive Remediation Combined With Open-Label Lurasidone in Patients With Schizophrenia and Schizoaffective Disorder.
Kantrowitz JT, Sharif Z, Medalia A, Keefe RS, Harvey P, Bruder G, Barch DM, Choo T, Lee S, Lieberman JA. Kantrowitz JT, et al. Among authors: lieberman ja. J Clin Psychiatry. 2016 Jun;77(6):799-806. doi: 10.4088/JCP.15m09998. J Clin Psychiatry. 2016. PMID: 27035157 Clinical Trial.
A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Tocilizumab, An Interleukin-6 Receptor Antibody, For Residual Symptoms in Schizophrenia.
Girgis RR, Ciarleglio A, Choo T, Haynes G, Bathon JM, Cremers S, Kantrowitz JT, Lieberman JA, Brown AS. Girgis RR, et al. Among authors: lieberman ja. Neuropsychopharmacology. 2018 May;43(6):1317-1323. doi: 10.1038/npp.2017.258. Epub 2017 Nov 1. Neuropsychopharmacology. 2018. PMID: 29090685 Free PMC article. Clinical Trial.
Double blind, two dose, randomized, placebo-controlled, cross-over clinical trial of the positive allosteric modulator at the alpha7 nicotinic cholinergic receptor AVL-3288 in schizophrenia patients.
Kantrowitz JT, Javitt DC, Freedman R, Sehatpour P, Kegeles LS, Carlson M, Sobeih T, Wall MM, Choo TH, Vail B, Grinband J, Lieberman JA. Kantrowitz JT, et al. Among authors: lieberman ja. Neuropsychopharmacology. 2020 Jul;45(8):1339-1345. doi: 10.1038/s41386-020-0628-9. Epub 2020 Feb 3. Neuropsychopharmacology. 2020. PMID: 32015461 Free PMC article. Clinical Trial.
Proof of mechanism and target engagement of glutamatergic drugs for the treatment of schizophrenia: RCTs of pomaglumetad and TS-134 on ketamine-induced psychotic symptoms and pharmacoBOLD in healthy volunteers.
Kantrowitz JT, Grinband J, Goff DC, Lahti AC, Marder SR, Kegeles LS, Girgis RR, Sobeih T, Wall MM, Choo TH, Green MF, Yang YS, Lee J, Horga G, Krystal JH, Potter WZ, Javitt DC, Lieberman JA. Kantrowitz JT, et al. Among authors: lieberman ja. Neuropsychopharmacology. 2020 Oct;45(11):1842-1850. doi: 10.1038/s41386-020-0706-z. Epub 2020 May 13. Neuropsychopharmacology. 2020. PMID: 32403118 Free PMC article. Clinical Trial.
Dr Kantrowitz and Colleagues Reply.
Kantrowitz JT, Medalia A, Keefe RS, Harvey PD, Bruder G, Barch DM, Choo T, Lee S, Lieberman JA. Kantrowitz JT, et al. Among authors: lieberman ja. J Clin Psychiatry. 2016 Oct;77(10):e1353. doi: 10.4088/JCP.16lr10887a. J Clin Psychiatry. 2016. PMID: 27788318 Free article. No abstract available.
Utility of Imaging-Based Biomarkers for Glutamate-Targeted Drug Development in Psychotic Disorders: A Randomized Clinical Trial.
Javitt DC, Carter CS, Krystal JH, Kantrowitz JT, Girgis RR, Kegeles LS, Ragland JD, Maddock RJ, Lesh TA, Tanase C, Corlett PR, Rothman DL, Mason G, Qiu M, Robinson J, Potter WZ, Carlson M, Wall MM, Choo TH, Grinband J, Lieberman JA. Javitt DC, et al. Among authors: lieberman ja. JAMA Psychiatry. 2018 Jan 1;75(1):11-19. doi: 10.1001/jamapsychiatry.2017.3572. JAMA Psychiatry. 2018. PMID: 29167877 Free PMC article. Clinical Trial.
810 results