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Dehydrocostus lactone suppresses osteoclast differentiation by regulating NFATc1 and inhibits osteoclast activation through modulating migration and lysosome function.
Lee HI, Lee J, Hwang D, Lee GR, Kim N, Kwon M, Lee H, Piao D, Kim HJ, Kim NY, Kim HS, Seo EK, Kang D, Jeong W. Lee HI, et al. Among authors: kim hj, kim n, kim ny, kim hs. FASEB J. 2019 Aug;33(8):9685-9694. doi: 10.1096/fj.201900862R. Epub 2019 May 30. FASEB J. 2019. PMID: 31145860
These results indicate that DL has therapeutic potential to treat bone diseases caused by excessive or hyperactive osteoclasts.-Lee, H. I., Lee, J., Hwang, D., Lee, G.-R., Kim, N., Kwon, M., Lee, H., Piao, D., Kim, H. J., Kim, N. Y., K …
These results indicate that DL has therapeutic potential to treat bone diseases caused by excessive or hyperactive osteoclasts.-Lee, H …
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