Hynes RO - Search Results

1

A framework for advancing our understanding of cancer-associated fibroblasts.

Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, Kolonin MG, Maki RG, Powers RS, Puré E, Ramirez DC, Scherz-Shouval R, Sherman MH, Stewart S, Tlsty TD, Tuveson DA, Watt FM, Weaver V, Weeraratna AT, Werb Z. Sahai E, et al. Among authors: hynes ro. Nat Rev Cancer. 2020 Mar;20(3):174-186. doi: 10.1038/s41568-019-0238-1. Epub 2020 Jan 24. Nat Rev Cancer. 2020. PMID: 31980749 Free PMC article. Review.

2

Rolling in P-selectin-deficient mice is reduced but not eliminated in the dorsal skin.

Yamada S, Mayadas TN, Yuan F, Wagner DD, Hynes RO, Melder RJ, Jain RK. Yamada S, et al. Among authors: hynes ro. Blood. 1995 Nov 1;86(9):3487-92. Blood. 1995. PMID: 7579454 Free article.

3

Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin.

Hamano Y, Zeisberg M, Sugimoto H, Lively JC, Maeshima Y, Yang C, Hynes RO, Werb Z, Sudhakar A, Kalluri R. Hamano Y, et al. Among authors: hynes ro. Cancer Cell. 2003 Jun;3(6):589-601. doi: 10.1016/s1535-6108(03)00133-8. Cancer Cell. 2003. PMID: 12842087 Free PMC article.

4

Proteomic analyses of ECM during pancreatic ductal adenocarcinoma progression reveal different contributions by tumor and stromal cells.

Tian C, Clauser KR, Öhlund D, Rickelt S, Huang Y, Gupta M, Mani DR, Carr SA, Tuveson DA, Hynes RO. Tian C, et al. Among authors: hynes ro. Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19609-19618. doi: 10.1073/pnas.1908626116. Epub 2019 Sep 4. Proc Natl Acad Sci U S A. 2019. PMID: 31484774 Free PMC article.

5

Proteomic Profiling of the ECM of Xenograft Breast Cancer Metastases in Different Organs Reveals Distinct Metastatic Niches.

Hebert JD, Myers SA, Naba A, Abbruzzese G, Lamar JM, Carr SA, Hynes RO. Hebert JD, et al. Among authors: hynes ro. Cancer Res. 2020 Apr 1;80(7):1475-1485. doi: 10.1158/0008-5472.CAN-19-2961. Epub 2020 Feb 4. Cancer Res. 2020. PMID: 32019869 Free PMC article.

6

Cancer Cell-Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma.

Tian C, Öhlund D, Rickelt S, Lidström T, Huang Y, Hao L, Zhao RT, Franklin O, Bhatia SN, Tuveson DA, Hynes RO. Tian C, et al. Among authors: hynes ro. Cancer Res. 2020 Apr 1;80(7):1461-1474. doi: 10.1158/0008-5472.CAN-19-2578. Epub 2020 Feb 6. Cancer Res. 2020. PMID: 32029550 Free PMC article.

7

Genomic analysis of metastasis reveals an essential role for RhoC.

Clark EA, Golub TR, Lander ES, Hynes RO. Clark EA, et al. Among authors: hynes ro. Nature. 2000 Aug 3;406(6795):532-5. doi: 10.1038/35020106. Nature. 2000. PMID: 10952316

8

Tumor-lymphatic interactions in an activated stromal microenvironment.

Wong SY, Hynes RO. Wong SY, et al. Among authors: hynes ro. J Cell Biochem. 2007 Jul 1;101(4):840-50. doi: 10.1002/jcb.21146. J Cell Biochem. 2007. PMID: 17177186 Review.

9

Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis.

Labelle M, Begum S, Hynes RO. Labelle M, et al. Among authors: hynes ro. Cancer Cell. 2011 Nov 15;20(5):576-90. doi: 10.1016/j.ccr.2011.09.009. Cancer Cell. 2011. PMID: 22094253 Free PMC article.

10

A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis.

Reticker-Flynn NE, Malta DF, Winslow MM, Lamar JM, Xu MJ, Underhill GH, Hynes RO, Jacks TE, Bhatia SN. Reticker-Flynn NE, et al. Among authors: hynes ro. Nat Commun. 2012;3:1122. doi: 10.1038/ncomms2128. Nat Commun. 2012. PMID: 23047680 Free PMC article.

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