Holst J - Search Results

1

Amino Acid Transporters and Exchangers from the SLC1A Family: Structure, Mechanism and Roles in Physiology and Cancer.

Freidman N, Chen I, Wu Q, Briot C, Holst J, Font J, Vandenberg R, Ryan R. Freidman N, et al. Among authors: holst j. Neurochem Res. 2020 Jun;45(6):1268-1286. doi: 10.1007/s11064-019-02934-x. Epub 2020 Jan 24. Neurochem Res. 2020. PMID: 31981058 Review.

2

Targeting glutamine transport to suppress melanoma cell growth.

Wang Q, Beaumont KA, Otte NJ, Font J, Bailey CG, van Geldermalsen M, Sharp DM, Tiffen JC, Ryan RM, Jormakka M, Haass NK, Rasko JE, Holst J. Wang Q, et al. Among authors: holst j. Int J Cancer. 2014 Sep 1;135(5):1060-71. doi: 10.1002/ijc.28749. Epub 2014 Feb 17. Int J Cancer. 2014. PMID: 24531984

3

Monoterpene glycoside ESK246 from Pittosporum targets LAT3 amino acid transport and prostate cancer cell growth.

Wang Q, Grkovic T, Font J, Bonham S, Pouwer RH, Bailey CG, Moran AM, Ryan RM, Rasko JE, Jormakka M, Quinn RJ, Holst J. Wang Q, et al. Among authors: holst j. ACS Chem Biol. 2014 Jun 20;9(6):1369-76. doi: 10.1021/cb500120x. Epub 2014 May 5. ACS Chem Biol. 2014. PMID: 24762008 Free PMC article.

4

Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways.

van Geldermalsen M, Quek LE, Turner N, Freidman N, Pang A, Guan YF, Krycer JR, Ryan R, Wang Q, Holst J. van Geldermalsen M, et al. Among authors: holst j. BMC Cancer. 2018 Jun 26;18(1):689. doi: 10.1186/s12885-018-4599-8. BMC Cancer. 2018. PMID: 29940911 Free PMC article.

5

Regulation of SLC1A4 and SLC1A5 in Prostate Cancer-Letter.

Ryan RM, Holst J. Ryan RM, et al. Among authors: holst j. Mol Cancer Res. 2018 Nov;16(11):1809-1810. doi: 10.1158/1541-7786.MCR-18-0239. Mol Cancer Res. 2018. PMID: 30385663 No abstract available.

6

Ablation of the ASCT2 (SLC1A5) gene encoding a neutral amino acid transporter reveals transporter plasticity and redundancy in cancer cells.

Bröer A, Gauthier-Coles G, Rahimi F, van Geldermalsen M, Dorsch D, Wegener A, Holst J, Bröer S. Bröer A, et al. Among authors: holst j. J Biol Chem. 2019 Mar 15;294(11):4012-4026. doi: 10.1074/jbc.RA118.006378. Epub 2019 Jan 11. J Biol Chem. 2019. PMID: 30635397 Free PMC article.

7

Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth.

Wang Q, Guan YF, Hancock SE, Wahi K, van Geldermalsen M, Zhang BK, Pang A, Nagarajah R, Mak B, Freidman N, Horvath LG, Turner N, Holst J. Wang Q, et al. Among authors: holst j. J Pathol. 2021 Jun;254(2):135-146. doi: 10.1002/path.5665. Epub 2021 Apr 21. J Pathol. 2021. PMID: 33768538

8

Macropinocytosis mediates resistance to loss of glutamine transport in triple-negative breast cancer.

Wahi K, Freidman N, Wang Q, Devadason M, Quek LE, Pang A, Lloyd L, Larance M, Zanini F, Harvey K, O'Toole S, Guan YF, Holst J. Wahi K, et al. Among authors: holst j. EMBO J. 2024 Oct 17. doi: 10.1038/s44318-024-00271-6. Online ahead of print. EMBO J. 2024. PMID: 39420093 Free article.

9

Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression.

Wang Q, Bailey CG, Ng C, Tiffen J, Thoeng A, Minhas V, Lehman ML, Hendy SC, Buchanan G, Nelson CC, Rasko JE, Holst J. Wang Q, et al. Among authors: holst j. Cancer Res. 2011 Dec 15;71(24):7525-36. doi: 10.1158/0008-5472.CAN-11-1821. Epub 2011 Oct 17. Cancer Res. 2011. PMID: 22007000

10

Targeting amino acid transport in metastatic castration-resistant prostate cancer: effects on cell cycle, cell growth, and tumor development.

Wang Q, Tiffen J, Bailey CG, Lehman ML, Ritchie W, Fazli L, Metierre C, Feng YJ, Li E, Gleave M, Buchanan G, Nelson CC, Rasko JE, Holst J. Wang Q, et al. Among authors: holst j. J Natl Cancer Inst. 2013 Oct 2;105(19):1463-73. doi: 10.1093/jnci/djt241. Epub 2013 Sep 19. J Natl Cancer Inst. 2013. PMID: 24052624

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