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Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28.
Müller I, Strozyk E, Schindler S, Beissert S, Oo HZ, Sauter T, Lucarelli P, Raeth S, Hausser A, Al Nakouzi N, Fazli L, Gleave ME, Liu H, Simon HU, Walczak H, Green DR, Bartek J, Daugaard M, Kulms D. Müller I, et al. Mol Cell. 2020 Mar 5;77(5):970-984.e7. doi: 10.1016/j.molcel.2019.12.023. Epub 2020 Jan 22. Mol Cell. 2020. PMID: 31982308 Free PMC article.
Potent pro-apoptotic combination therapy is highly effective in a broad range of cancers.
Montinaro A, Areso Zubiaur I, Saggau J, Kretz AL, Ferreira RMM, Hassan O, Kitzig E, Müller I, El-Bahrawy MA, von Karstedt S, Kulms D, Liccardi G, Lemke J, Walczak H. Montinaro A, et al. Among authors: muller i. Cell Death Differ. 2022 Mar;29(3):492-503. doi: 10.1038/s41418-021-00869-x. Epub 2021 Sep 17. Cell Death Differ. 2022. PMID: 34535764 Free PMC article.
Superior Properties of Fc-comprising scTRAIL Fusion Proteins.
Hutt M, Marquardt L, Seifert O, Siegemund M, Müller I, Kulms D, Pfizenmaier K, Kontermann RE. Hutt M, et al. Among authors: muller i. Mol Cancer Ther. 2017 Dec;16(12):2792-2802. doi: 10.1158/1535-7163.MCT-17-0551. Epub 2017 Sep 13. Mol Cancer Ther. 2017. PMID: 28904131
IgG-single-chain TRAIL fusion proteins for tumour therapy.
Siegemund M, Schneider F, Hutt M, Seifert O, Müller I, Kulms D, Pfizenmaier K, Kontermann RE. Siegemund M, et al. Among authors: muller i. Sci Rep. 2018 May 17;8(1):7808. doi: 10.1038/s41598-018-24450-8. Sci Rep. 2018. PMID: 29773864 Free PMC article.
The Use of MPS in Three Rs and Regulatory Applications: Perspectives From Developers on Stakeholder Responsibilities.
LaFollette MR, Baran SW, Curley JL, Dickinson AM, Frazier T, Hobi N, Huang MI, Hutter V, Maisonneuve BGC, Marsh GA, Mahendran R, Müller I, Qian X, Singh D, Thelin WR, Vukasinovic J, Candarlioglu PL, Roper CS. LaFollette MR, et al. Among authors: muller i. Altern Lab Anim. 2025 Jan;53(1):26-41. doi: 10.1177/02611929241310566. Altern Lab Anim. 2025. PMID: 39772941 Review.
1,273 results