Pirrone GF - Search Results

1

Liposome Artificial Membrane Permeability Assay by MALDI-hydrogen-deuterium exchange mass spectrometry for peptides and small proteins.

Makarov AA, Pirrone GF, Shchurik V, Regalado EL, Mangion I. Makarov AA, et al. Among authors: pirrone gf. Anal Chim Acta. 2020 Feb 22;1099:111-118. doi: 10.1016/j.aca.2019.09.063. Epub 2019 Sep 25. Anal Chim Acta. 2020. PMID: 31986267

2

Use of MALDI-MS Combined with Differential Hydrogen-Deuterium Exchange for Semiautomated Protein Global Conformational Screening.

Pirrone GF, Wang H, Canfield N, Chin AS, Rhodes TA, Makarov AA. Pirrone GF, et al. Anal Chem. 2017 Aug 15;89(16):8351-8357. doi: 10.1021/acs.analchem.7b01590. Epub 2017 Aug 4. Anal Chem. 2017. PMID: 28727449

3

Supercritical fluid chromatography-photodiode array detection-electrospray ionization mass spectrometry as a framework for impurity fate mapping in the development and manufacture of drug substances.

Pirrone GF, Mathew RM, Makarov AA, Bernardoni F, Klapars A, Hartman R, Limanto J, Regalado EL. Pirrone GF, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Mar 30;1080:42-49. doi: 10.1016/j.jchromb.2018.02.006. Epub 2018 Feb 8. J Chromatogr B Analyt Technol Biomed Life Sci. 2018. PMID: 29477066

4

Visualizing and studying frictional heating effects in reversed-phase liquid chromatography using infrared thermal imaging.

Makarov AA, Mann BF, Regalado EL, Pirrone GF, Sun C, Sun S, Nowak T, Wang H, Mangion I. Makarov AA, et al. Among authors: pirrone gf. Anal Chim Acta. 2018 Aug 14;1018:1-6. doi: 10.1016/j.aca.2018.02.061. Epub 2018 Mar 9. Anal Chim Acta. 2018. PMID: 29605126

5

Combination of circular dichroism spectroscopy and size-exclusion chromatography coupled with HDX-MS for studying global conformational structures of peptides in solution.

Schiavone NM, Pirrone GF, Guetschow ED, Mangion I, Makarov AA. Schiavone NM, et al. Among authors: pirrone gf. Talanta. 2019 Mar 1;194:177-182. doi: 10.1016/j.talanta.2018.09.077. Epub 2018 Sep 25. Talanta. 2019. PMID: 30609519

6

Use of MALDI-MS with solid-state hydrogen deuterium exchange for semi-automated assessment of peptide and protein physical stability in lyophilized solids.

Kabaria SR, Mangion I, Makarov AA, Pirrone GF. Kabaria SR, et al. Among authors: pirrone gf. Anal Chim Acta. 2019 Apr 25;1054:114-121. doi: 10.1016/j.aca.2018.12.034. Epub 2019 Jan 9. Anal Chim Acta. 2019. PMID: 30712581

7

Evaluation of global conformational changes in peptides and proteins following purification by supercritical fluid chromatography.

Schiavone NM, Bennett R, Hicks MB, Pirrone GF, Regalado EL, Mangion I, Makarov AA. Schiavone NM, et al. Among authors: pirrone gf. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Mar 15;1110-1111:94-100. doi: 10.1016/j.jchromb.2019.02.012. Epub 2019 Feb 13. J Chromatogr B Analyt Technol Biomed Life Sci. 2019. PMID: 30785083

8

Multi-column ultra-high performance liquid chromatography screening with chaotropic agents and computer-assisted separation modeling enables process development of new drug substances.

Haidar Ahmad IA , Chen W , Halsey HM , Klapars A , Limanto J , Pirrone GF , Nowak T , Bennett R , Hartman R , Makarov AA , Mangion I , Regalado EL . Haidar Ahmad IA , et al. Among authors: pirrone gf. Analyst. 2019 Apr 23;144(9):2872-2880. doi: 10.1039/c8an02499e. Analyst. 2019. PMID: 30830135

9

Combination of HDX-MS and in silico modeling to study enzymatic reactivity and stereo-selectivity at different solvent conditions.

Makarov AA, Iacob RE, Pirrone GF, Rodriguez-Granillo A, Joyce L, Mangion I, Moore JC, Sherer EC, Engen JR. Makarov AA, et al. Among authors: pirrone gf. J Pharm Biomed Anal. 2020 Apr 15;182:113141. doi: 10.1016/j.jpba.2020.113141. Epub 2020 Feb 1. J Pharm Biomed Anal. 2020. PMID: 32036298

10

Ultra-high-throughput SPE-MALDI workflow: Blueprint for efficient purification and screening of peptide libraries.

Bennett R, Pirrone GF, Nowak T, Mukherjee D, Shchurik V, Mapelli C, Hickey JL, Regalado EL, Mangion I, Makarov AA. Bennett R, et al. Among authors: pirrone gf. Anal Chim Acta. 2021 Jan 15;1142:10-18. doi: 10.1016/j.aca.2020.10.045. Epub 2020 Oct 28. Anal Chim Acta. 2021. PMID: 33280687

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