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Bridging in vitro dissolution and in vivo exposure for acalabrutinib. Part II. A mechanistic PBPK model for IR formulation comparison, proton pump inhibitor drug interactions, and administration with acidic juices.
Pepin XJH, Moir AJ, Mann JC, Sanderson NJ, Barker R, Meehan E, Plumb AP, Bailey GR, Murphy DS, Krejsa CM, Andrew MA, Ingallinera TG, Slatter JG. Pepin XJH, et al. Among authors: meehan e. Eur J Pharm Biopharm. 2019 Sep;142:435-448. doi: 10.1016/j.ejpb.2019.07.011. Epub 2019 Jul 12. Eur J Pharm Biopharm. 2019. PMID: 31306750
Linked experimental and modelling approaches for tablet property predictions.
Jolliffe HG, Ojo E, Mendez C, Houson I, Elkes R, Reynolds G, Kong A, Meehan E, Becker FA, Piccione PM, Verma S, Singaraju A, Halbert G, Robertson J. Jolliffe HG, et al. Among authors: meehan e. Int J Pharm. 2022 Oct 15;626:122116. doi: 10.1016/j.ijpharm.2022.122116. Epub 2022 Aug 18. Int J Pharm. 2022. PMID: 35987318 Free article.
134 results