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Dynamic Shifts in the HIV Proviral Landscape During Long Term Combination Antiretroviral Therapy: Implications for Persistence and Control of HIV Infections.
Anderson EM, Simonetti FR, Gorelick RJ, Hill S, Gouzoulis MA, Bell J, Rehm C, Pérez L, Boritz E, Wu X, Wells D, Hughes SH, Rao V, Coffin JM, Kearney MF, Maldarelli F. Anderson EM, et al. Among authors: simonetti fr. Viruses. 2020 Jan 25;12(2):136. doi: 10.3390/v12020136. Viruses. 2020. PMID: 31991737 Free PMC article.
Review: Influence of ART on HIV genetics.
Simonetti FR, Kearney MF. Simonetti FR, et al. Curr Opin HIV AIDS. 2015 Jan;10(1):49-54. doi: 10.1097/COH.0000000000000120. Curr Opin HIV AIDS. 2015. PMID: 25389802 Free PMC article. Review.
Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo.
Simonetti FR, Sobolewski MD, Fyne E, Shao W, Spindler J, Hattori J, Anderson EM, Watters SA, Hill S, Wu X, Wells D, Su L, Luke BT, Halvas EK, Besson G, Penrose KJ, Yang Z, Kwan RW, Van Waes C, Uldrick T, Citrin DE, Kovacs J, Polis MA, Rehm CA, Gorelick R, Piatak M, Keele BF, Kearney MF, Coffin JM, Hughes SH, Mellors JW, Maldarelli F. Simonetti FR, et al. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1883-8. doi: 10.1073/pnas.1522675113. Epub 2016 Feb 8. Proc Natl Acad Sci U S A. 2016. PMID: 26858442 Free PMC article.
Clones of infected cells arise early in HIV-infected individuals.
Coffin JM, Wells DW, Zerbato JM, Kuruc JD, Guo S, Luke BT, Eron JJ, Bale M, Spindler J, Simonetti FR, Hill S, Kearney MF, Maldarelli F, Wu X, Mellors JW, Hughes SH. Coffin JM, et al. Among authors: simonetti fr. JCI Insight. 2019 Jun 20;4(12):e128432. doi: 10.1172/jci.insight.128432. eCollection 2019 Jun 20. JCI Insight. 2019. PMID: 31217357 Free PMC article.
The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections.
Bender AM, Simonetti FR, Kumar MR, Fray EJ, Bruner KM, Timmons AE, Tai KY, Jenike KM, Antar AAR, Liu PT, Ho YC, Raugi DN, Seydi M, Gottlieb GS, Okoye AA, Del Prete GQ, Picker LJ, Mankowski JL, Lifson JD, Siliciano JD, Laird GM, Barouch DH, Clements JE, Siliciano RF. Bender AM, et al. Among authors: simonetti fr. Cell Host Microbe. 2019 Jul 10;26(1):73-85.e4. doi: 10.1016/j.chom.2019.06.005. Cell Host Microbe. 2019. PMID: 31295427 Free PMC article.
No evidence of ongoing HIV replication or compartmentalization in tissues during combination antiretroviral therapy: Implications for HIV eradication.
Bozzi G, Simonetti FR, Watters SA, Anderson EM, Gouzoulis M, Kearney MF, Rote P, Lange C, Shao W, Gorelick R, Fullmer B, Kumar S, Wank S, Hewitt S, Kleiner DE, Hattori J, Bale MJ, Hill S, Bell J, Rehm C, Grossman Z, Yarchoan R, Uldrick T, Maldarelli F. Bozzi G, et al. Among authors: simonetti fr. Sci Adv. 2019 Sep 25;5(9):eaav2045. doi: 10.1126/sciadv.aav2045. eCollection 2019 Sep. Sci Adv. 2019. PMID: 31579817 Free PMC article.
HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus.
Musick A, Spindler J, Boritz E, Pérez L, Crespo-Vélez D, Patro SC, Sobolewski MD, Bale MJ, Reid C, Keele BF, Capoferri A, Shao W, Wiegand A, Simonetti FR, Mellors JW, Hughes SH, Coffin JM, Maldarelli F, Kearney MF. Musick A, et al. Among authors: simonetti fr. Front Microbiol. 2019 Oct 1;10:2204. doi: 10.3389/fmicb.2019.02204. eCollection 2019. Front Microbiol. 2019. PMID: 31632364 Free PMC article.
'Rinse and Replace': Boosting T Cell Turnover To Reduce HIV-1 Reservoirs.
Grossman Z, Singh NJ, Simonetti FR, Lederman MM, Douek DC, Deeks SG; Contributing authors. Grossman Z, et al. Among authors: simonetti fr. Trends Immunol. 2020 Jun;41(6):466-480. doi: 10.1016/j.it.2020.04.003. Epub 2020 May 12. Trends Immunol. 2020. PMID: 32414695 Review.
46 results