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A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows Prediction of Human Brain Target Site Concentrations.
Yamamoto Y, Välitalo PA, van den Berg DJ, Hartman R, van den Brink W, Wong YC, Huntjens DR, Proost JH, Vermeulen A, Krauwinkel W, Bakshi S, Aranzana-Climent V, Marchand S, Dahyot-Fizelier C, Couet W, Danhof M, van Hasselt JG, de Lange EC. Yamamoto Y, et al. Pharm Res. 2017 Feb;34(2):333-351. doi: 10.1007/s11095-016-2065-3. Epub 2016 Nov 18. Pharm Res. 2017. PMID: 27864744 Free PMC article.
Clinical Pharmacokinetics and Pharmacodynamics of Colistin.
Grégoire N, Aranzana-Climent V, Magréault S, Marchand S, Couet W. Grégoire N, et al. Clin Pharmacokinet. 2017 Dec;56(12):1441-1460. doi: 10.1007/s40262-017-0561-1. Clin Pharmacokinet. 2017. PMID: 28550595 Review.
Efficacy of EBL-1003 (apramycin) against Acinetobacter baumannii lung infections in mice.
Becker K, Aranzana-Climent V, Cao S, Nilsson A, Shariatgorji R, Haldimann K, Platzack B, Hughes D, Andrén PE, Böttger EC, Friberg LE, Hobbie SN; ENABLE consortium. Becker K, et al. Clin Microbiol Infect. 2021 Sep;27(9):1315-1321. doi: 10.1016/j.cmi.2020.12.004. Epub 2020 Dec 11. Clin Microbiol Infect. 2021. PMID: 33316399 Free article.
Translational in vitro and in vivo PKPD modelling for apramycin against Gram-negative lung pathogens to facilitate prediction of human efficacious dose in pneumonia.
Aranzana-Climent V, Hughes D, Cao S, Tomczak M, Urbas M, Zabicka D, Vingsbo Lundberg C, Hansen J, Lindberg J, Hobbie SN, Friberg LE. Aranzana-Climent V, et al. Clin Microbiol Infect. 2022 Oct;28(10):1367-1374. doi: 10.1016/j.cmi.2022.05.003. Epub 2022 May 20. Clin Microbiol Infect. 2022. PMID: 35598857 Free article.
16 results