Bassik MC - Search Results

1

Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway.

Dubreuil MM, Morgens DW, Okumoto K, Honsho M, Contrepois K, Lee-McMullen B, Traber GM, Sood RS, Dixon SJ, Snyder MP, Fujiki Y, Bassik MC. Dubreuil MM, et al. Among authors: bassik mc. Cell Rep. 2020 Feb 4;30(5):1417-1433.e7. doi: 10.1016/j.celrep.2020.01.013. Cell Rep. 2020. PMID: 32023459 Free PMC article.

2

Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment.

Meng X, Yao D, Imaizumi K, Chen X, Kelley KW, Reis N, Thete MV, Arjun McKinney A, Kulkarni S, Panagiotakos G, Bassik MC, Pașca SP. Meng X, et al. Among authors: bassik mc. Nature. 2023 Oct;622(7982):359-366. doi: 10.1038/s41586-023-06564-w. Epub 2023 Sep 27. Nature. 2023. PMID: 37758944 Free PMC article.

3

Cell volume expansion and local contractility drive collective invasion of the basement membrane in breast cancer.

Chang J, Saraswathibhatla A, Song Z, Varma S, Sanchez C, Alyafei NHK, Indana D, Slyman R, Srivastava S, Liu K, Bassik MC, Marinkovich MP, Hodgson L, Shenoy V, West RB, Chaudhuri O. Chang J, et al. Among authors: bassik mc. Nat Mater. 2024 May;23(5):711-722. doi: 10.1038/s41563-023-01716-9. Epub 2023 Nov 13. Nat Mater. 2024. PMID: 37957268 Free PMC article.

4

Single-molecule imaging reveals distinct elongation and frameshifting dynamics between frames of expanded RNA repeats in C9ORF72-ALS/FTD.

Latallo MJ, Wang S, Dong D, Nelson B, Livingston NM, Wu R, Zhao N, Stasevich TJ, Bassik MC, Sun S, Wu B. Latallo MJ, et al. Among authors: bassik mc. Nat Commun. 2023 Sep 11;14(1):5581. doi: 10.1038/s41467-023-41339-x. Nat Commun. 2023. PMID: 37696852 Free PMC article.

5

A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience.

Wang C, Wang B, Pandey T, Long Y, Zhang J, Oh F, Sima J, Guo R, Liu Y, Zhang C, Mukherjee S, Bassik M, Lin W, Deng H, Vale G, McDonald JG, Shen K, Ma DK. Wang C, et al. Nat Commun. 2022 Nov 10;13(1):6805. doi: 10.1038/s41467-022-34450-y. Nat Commun. 2022. PMID: 36357390 Free PMC article.

6

Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification.

Deans RM, Morgens DW, Ökesli A, Pillay S, Horlbeck MA, Kampmann M, Gilbert LA, Li A, Mateo R, Smith M, Glenn JS, Carette JE, Khosla C, Bassik MC. Deans RM, et al. Among authors: bassik mc. Nat Chem Biol. 2016 May;12(5):361-6. doi: 10.1038/nchembio.2050. Epub 2016 Mar 28. Nat Chem Biol. 2016. PMID: 27018887 Free PMC article.

7

Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes.

Morgens DW, Deans RM, Li A, Bassik MC. Morgens DW, et al. Among authors: bassik mc. Nat Biotechnol. 2016 Jun;34(6):634-6. doi: 10.1038/nbt.3567. Epub 2016 May 9. Nat Biotechnol. 2016. PMID: 27159373 Free PMC article.

8

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

Han K, Jeng EE, Hess GT, Morgens DW, Li A, Bassik MC. Han K, et al. Among authors: bassik mc. Nat Biotechnol. 2017 May;35(5):463-474. doi: 10.1038/nbt.3834. Epub 2017 Mar 20. Nat Biotechnol. 2017. PMID: 28319085 Free PMC article.

9

Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens.

Morgens DW, Wainberg M, Boyle EA, Ursu O, Araya CL, Tsui CK, Haney MS, Hess GT, Han K, Jeng EE, Li A, Snyder MP, Greenleaf WJ, Kundaje A, Bassik MC. Morgens DW, et al. Among authors: bassik mc. Nat Commun. 2017 May 5;8:15178. doi: 10.1038/ncomms15178. Nat Commun. 2017. PMID: 28474669 Free PMC article.

10

CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity.

Burr ML, Sparbier CE, Chan YC, Williamson JC, Woods K, Beavis PA, Lam EYN, Henderson MA, Bell CC, Stolzenburg S, Gilan O, Bloor S, Noori T, Morgens DW, Bassik MC, Neeson PJ, Behren A, Darcy PK, Dawson SJ, Voskoboinik I, Trapani JA, Cebon J, Lehner PJ, Dawson MA. Burr ML, et al. Among authors: bassik mc. Nature. 2017 Sep 7;549(7670):101-105. doi: 10.1038/nature23643. Epub 2017 Aug 16. Nature. 2017. PMID: 28813417 Free PMC article.

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