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p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells.
Tarangelo A, Magtanong L, Bieging-Rolett KT, Li Y, Ye J, Attardi LD, Dixon SJ. Tarangelo A, et al. Among authors: dixon sj. Cell Rep. 2018 Jan 16;22(3):569-575. doi: 10.1016/j.celrep.2017.12.077. Cell Rep. 2018. PMID: 29346757 Free PMC article.
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.
Bersuker K, Hendricks JM, Li Z, Magtanong L, Ford B, Tang PH, Roberts MA, Tong B, Maimone TJ, Zoncu R, Bassik MC, Nomura DK, Dixon SJ, Olzmann JA. Bersuker K, et al. Among authors: dixon sj. Nature. 2019 Nov;575(7784):688-692. doi: 10.1038/s41586-019-1705-2. Epub 2019 Oct 21. Nature. 2019. PMID: 31634900 Free PMC article.
Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells.
Johnson FD, Ferrarone J, Liu A, Brandstädter C, Munuganti R, Farnsworth DA, Lu D, Luu J, Sihota T, Jansen S, Nagelberg A, Shi R, Forcina GC, Zhang X, Cheng GSW, Spencer Miko SE, de Rappard-Yuswack G, Sorensen PH, Dixon SJ, Guha U, Becker K, Djaballah H, Somwar R, Varmus H, Morin GB, Lockwood WW. Johnson FD, et al. Among authors: dixon sj. Cell Rep. 2022 Feb 8;38(6):110343. doi: 10.1016/j.celrep.2022.110343. Cell Rep. 2022. PMID: 35139387 Free PMC article.
Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability.
Li Z, Ferguson L, Deol KK, Roberts MA, Magtanong L, Hendricks JM, Mousa GA, Kilinc S, Schaefer K, Wells JA, Bassik MC, Goga A, Dixon SJ, Ingolia NT, Olzmann JA. Li Z, et al. Among authors: dixon sj. Nat Chem Biol. 2022 Jul;18(7):751-761. doi: 10.1038/s41589-022-01033-3. Epub 2022 May 30. Nat Chem Biol. 2022. PMID: 35637349 Free PMC article.
Lipid droplets and peroxisomes are co-regulated to drive lifespan extension in response to mono-unsaturated fatty acids.
Papsdorf K, Miklas JW, Hosseini A, Cabruja M, Morrow CS, Savini M, Yu Y, Silva-García CG, Haseley NR, Murphy LM, Yao P, de Launoit E, Dixon SJ, Snyder MP, Wang MC, Mair WB, Brunet A. Papsdorf K, et al. Among authors: dixon sj. Nat Cell Biol. 2023 May;25(5):672-684. doi: 10.1038/s41556-023-01136-6. Epub 2023 May 1. Nat Cell Biol. 2023. PMID: 37127715 Free PMC article.
Author Correction: Lipid droplets and peroxisomes are co-regulated to drive lifespan extension in response to mono-unsaturated fatty acids.
Papsdorf K, Miklas JW, Hosseini A, Cabruja M, Morrow CS, Savini M, Yu Y, Silva-García CG, Haseley NR, Murphy LM, Yao P, de Launoit E, Dixon SJ, Snyder MP, Wang MC, Mair WB, Brunet A. Papsdorf K, et al. Among authors: dixon sj. Nat Cell Biol. 2023 Oct;25(10):1547. doi: 10.1038/s41556-023-01220-x. Nat Cell Biol. 2023. PMID: 37567997 Free PMC article. No abstract available.
Death-seq identifies regulators of cell death and senolytic therapies.
Colville A, Liu JY, Rodriguez-Mateo C, Thomas S, Ishak HD, Zhou R, Klein JDD, Morgens DW, Goshayeshi A, Salvi JS, Yao D, Spees K, Dixon SJ, Liu C, Rhee JW, Lai C, Wu JC, Bassik MC, Rando TA. Colville A, et al. Among authors: dixon sj. Cell Metab. 2023 Oct 3;35(10):1814-1829.e6. doi: 10.1016/j.cmet.2023.08.008. Epub 2023 Sep 11. Cell Metab. 2023. PMID: 37699398 Free PMC article.
Heat stress induces ferroptosis-like cell death in plants.
Distéfano AM, Martin MV, Córdoba JP, Bellido AM, D'Ippólito S, Colman SL, Soto D, Roldán JA, Bartoli CG, Zabaleta EJ, Fiol DF, Stockwell BR, Dixon SJ, Pagnussat GC. Distéfano AM, et al. Among authors: dixon sj. J Cell Biol. 2017 Feb;216(2):463-476. doi: 10.1083/jcb.201605110. Epub 2017 Jan 18. J Cell Biol. 2017. PMID: 28100685 Free PMC article.
268 results