Zhang R - Search Results

1

Epigenetic driver mutations in ARID1A shape cancer immune phenotype and immunotherapy.

Li J, Wang W, Zhang Y, Cieślik M, Guo J, Tan M, Green MD, Wang W, Lin H, Li W, Wei S, Zhou J, Li G, Jing X, Vatan L, Zhao L, Bitler B, Zhang R, Cho KR, Dou Y, Kryczek I, Chan TA, Huntsman D, Chinnaiyan AM, Zou W. Li J, et al. Among authors: zhang r, zhang y. J Clin Invest. 2020 May 1;130(5):2712-2726. doi: 10.1172/JCI134402. J Clin Invest. 2020. PMID: 32027624 Free PMC article.

2

Wnt5a suppresses epithelial ovarian cancer by promoting cellular senescence.

Bitler BG, Nicodemus JP, Li H, Cai Q, Wu H, Hua X, Li T, Birrer MJ, Godwin AK, Cairns P, Zhang R. Bitler BG, et al. Among authors: zhang r. Cancer Res. 2011 Oct 1;71(19):6184-94. doi: 10.1158/0008-5472.CAN-11-1341. Epub 2011 Aug 4. Cancer Res. 2011. PMID: 21816908 Free PMC article.

3

Oncogenic RAS regulates BRIP1 expression to induce dissociation of BRCA1 from chromatin, inhibit DNA repair, and promote senescence.

Tu Z, Aird KM, Bitler BG, Nicodemus JP, Beeharry N, Xia B, Yen TJ, Zhang R. Tu Z, et al. Among authors: zhang r. Dev Cell. 2011 Dec 13;21(6):1077-91. doi: 10.1016/j.devcel.2011.10.010. Epub 2011 Dec 1. Dev Cell. 2011. PMID: 22137763 Free PMC article.

4

ALDH1A1 is a novel EZH2 target gene in epithelial ovarian cancer identified by genome-wide approaches.

Li H, Bitler BG, Vathipadiekal V, Maradeo ME, Slifker M, Creasy CL, Tummino PJ, Cairns P, Birrer MJ, Zhang R. Li H, et al. Among authors: zhang r. Cancer Prev Res (Phila). 2012 Mar;5(3):484-91. doi: 10.1158/1940-6207.CAPR-11-0414. Epub 2011 Dec 5. Cancer Prev Res (Phila). 2012. PMID: 22144423 Free PMC article.

5

NF-YA underlies EZH2 upregulation and is essential for proliferation of human epithelial ovarian cancer cells.

Garipov A, Li H, Bitler BG, Thapa RJ, Balachandran S, Zhang R. Garipov A, et al. Among authors: zhang r. Mol Cancer Res. 2013 Apr;11(4):360-9. doi: 10.1158/1541-7786.MCR-12-0661. Epub 2013 Jan 29. Mol Cancer Res. 2013. PMID: 23360797 Free PMC article.

6

Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence.

Aird KM, Zhang G, Li H, Tu Z, Bitler BG, Garipov A, Wu H, Wei Z, Wagner SN, Herlyn M, Zhang R. Aird KM, et al. Among authors: zhang r, zhang g. Cell Rep. 2013 Apr 25;3(4):1252-65. doi: 10.1016/j.celrep.2013.03.004. Epub 2013 Apr 4. Cell Rep. 2013. PMID: 23562156 Free PMC article.

7

A high-content screening assay for small-molecule modulators of oncogene-induced senescence.

Bitler BG, Fink LS, Wei Z, Peterson JR, Zhang R. Bitler BG, et al. Among authors: zhang r. J Biomol Screen. 2013 Oct;18(9):1054-61. doi: 10.1177/1087057113491827. Epub 2013 Jun 3. J Biomol Screen. 2013. PMID: 23733845 Free PMC article.

8

Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers.

Bitler BG, Aird KM, Garipov A, Li H, Amatangelo M, Kossenkov AV, Schultz DC, Liu Q, Shih IeM, Conejo-Garcia JR, Speicher DW, Zhang R. Bitler BG, et al. Among authors: zhang r. Nat Med. 2015 Mar;21(3):231-8. doi: 10.1038/nm.3799. Epub 2015 Feb 16. Nat Med. 2015. PMID: 25686104 Free PMC article.

9

Potential therapeutic targets in ARID1A-mutated cancers.

Bitler BG, Fatkhutdinov N, Zhang R. Bitler BG, et al. Among authors: zhang r. Expert Opin Ther Targets. 2015;19(11):1419-22. doi: 10.1517/14728222.2015.1062879. Epub 2015 Jun 30. Expert Opin Ther Targets. 2015. PMID: 26125128 Free PMC article. Review.

10

SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase.

Zhu H, Ren S, Bitler BG, Aird KM, Tu Z, Skordalakes E, Zhu Y, Yan J, Sun Y, Zhang R. Zhu H, et al. Among authors: zhang r. Cell Rep. 2015 Nov 10;13(6):1183-1193. doi: 10.1016/j.celrep.2015.09.083. Epub 2015 Oct 29. Cell Rep. 2015. PMID: 26527005 Free PMC article.

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