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mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia.
Paolella LM, Mukherjee S, Tran CM, Bellaver B, Hugo M, Luongo TS, Shewale SV, Lu W, Chellappa K, Baur JA. Paolella LM, et al. Among authors: luongo ts. Mol Metab. 2020 Feb;32:136-147. doi: 10.1016/j.molmet.2019.12.003. Epub 2019 Dec 13. Mol Metab. 2020. PMID: 32029223 Free PMC article.
SLC25A51 is a mammalian mitochondrial NAD+ transporter.
Luongo TS, Eller JM, Lu MJ, Niere M, Raith F, Perry C, Bornstein MR, Oliphint P, Wang L, McReynolds MR, Migaud ME, Rabinowitz JD, Johnson FB, Johnsson K, Ziegler M, Cambronne XA, Baur JA. Luongo TS, et al. Nature. 2020 Dec;588(7836):174-179. doi: 10.1038/s41586-020-2741-7. Epub 2020 Sep 9. Nature. 2020. PMID: 32906142 Free PMC article.
Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+ biosynthesis and sustain cardiac function.
Dierickx P, Zhu K, Carpenter BJ, Jiang C, Vermunt MW, Xiao Y, Luongo TS, Yamamoto T, Martí-Pàmies Í, Mia S, Latimer M, Diwan A, Zhao J, Hauck AK, Krusen B, Nguyen HCB, Blobel GA, Kelly DP, Pei L, Baur JA, Young ME, Lazar MA. Dierickx P, et al. Among authors: luongo ts. Nat Cardiovasc Res. 2022 Jan;1(1):45-58. doi: 10.1038/s44161-021-00001-9. Epub 2021 Dec 23. Nat Cardiovasc Res. 2022. PMID: 35036997 Free PMC article.
The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability.
Luongo TS, Lambert JP, Gross P, Nwokedi M, Lombardi AA, Shanmughapriya S, Carpenter AC, Kolmetzky D, Gao E, van Berlo JH, Tsai EJ, Molkentin JD, Chen X, Madesh M, Houser SR, Elrod JW. Luongo TS, et al. Nature. 2017 May 4;545(7652):93-97. doi: 10.1038/nature22082. Epub 2017 Apr 26. Nature. 2017. PMID: 28445457 Free PMC article.
22 results