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Page 1
mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia.
Paolella LM, Mukherjee S, Tran CM, Bellaver B, Hugo M, Luongo TS, Shewale SV, Lu W, Chellappa K, Baur JA. Paolella LM, et al. Among authors: shewale sv. Mol Metab. 2020 Feb;32:136-147. doi: 10.1016/j.molmet.2019.12.003. Epub 2019 Dec 13. Mol Metab. 2020. PMID: 32029223 Free PMC article.
Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure.
Murashige D, Jung JW, Neinast MD, Levin MG, Chu Q, Lambert JP, Garbincius JF, Kim B, Hoshino A, Marti-Pamies I, McDaid KS, Shewale SV, Flam E, Yang S, Roberts E, Li L, Morley MP, Bedi KC Jr, Hyman MC, Frankel DS, Margulies KB, Assoian RK, Elrod JW, Jang C, Rabinowitz JD, Arany Z. Murashige D, et al. Among authors: shewale sv. Cell Metab. 2022 Nov 1;34(11):1749-1764.e7. doi: 10.1016/j.cmet.2022.09.008. Epub 2022 Oct 11. Cell Metab. 2022. PMID: 36223763 Free PMC article.
Reduced Apolipoprotein M and Adverse Outcomes Across the Spectrum of Human Heart Failure.
Chirinos JA, Zhao L, Jia Y, Frej C, Adamo L, Mann D, Shewale SV, Millar JS, Rader DJ, French B, Brandimarto J, Margulies KB, Parks JS, Wang Z, Seiffert DA, Fang J, Sweitzer N, Chistoffersen C, Dahlbäck B, Car BD, Gordon DA, Cappola TP, Javaheri A. Chirinos JA, et al. Among authors: shewale sv. Circulation. 2020 May 5;141(18):1463-1476. doi: 10.1161/CIRCULATIONAHA.119.045323. Epub 2020 Apr 2. Circulation. 2020. PMID: 32237898 Free PMC article.
Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure.
Yurista SR, Matsuura TR, Silljé HHW, Nijholt KT, McDaid KS, Shewale SV, Leone TC, Newman JC, Verdin E, van Veldhuisen DJ, de Boer RA, Kelly DP, Westenbrink BD. Yurista SR, et al. Among authors: shewale sv. Circ Heart Fail. 2021 Jan;14(1):e007684. doi: 10.1161/CIRCHEARTFAILURE.120.007684. Epub 2020 Dec 28. Circ Heart Fail. 2021. PMID: 33356362 Free PMC article.
CAR T cells produced in vivo to treat cardiac injury.
Rurik JG, Tombácz I, Yadegari A, Méndez Fernández PO, Shewale SV, Li L, Kimura T, Soliman OY, Papp TE, Tam YK, Mui BL, Albelda SM, Puré E, June CH, Aghajanian H, Weissman D, Parhiz H, Epstein JA. Rurik JG, et al. Among authors: shewale sv. Science. 2022 Jan 7;375(6576):91-96. doi: 10.1126/science.abm0594. Epub 2022 Jan 6. Science. 2022. PMID: 34990237 Free PMC article.
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