Chen L - Search Results

1

Cis- and trans-regulations of pre-mRNA splicing by RNA editing enzymes influence cancer development.

Tang SJ, Shen H, An O, Hong H, Li J, Song Y, Han J, Tay DJT, Ng VHE, Bellido Molias F, Leong KW, Pitcheshwar P, Yang H, Chen L. Tang SJ, et al. Among authors: chen l. Nat Commun. 2020 Feb 7;11(1):799. doi: 10.1038/s41467-020-14621-5. Nat Commun. 2020. PMID: 32034135 Free PMC article.

2

Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma.

Chen L, Li Y, Lin CH, Chan TH, Chow RK, Song Y, Liu M, Yuan YF, Fu L, Kong KL, Qi L, Li Y, Zhang N, Tong AH, Kwong DL, Man K, Lo CM, Lok S, Tenen DG, Guan XY. Chen L, et al. Nat Med. 2013 Feb;19(2):209-16. doi: 10.1038/nm.3043. Epub 2013 Jan 6. Nat Med. 2013. PMID: 23291631 Free PMC article.

3

A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma.

Chan TH, Lin CH, Qi L, Fei J, Li Y, Yong KJ, Liu M, Song Y, Chow RK, Ng VH, Yuan YF, Tenen DG, Guan XY, Chen L. Chan TH, et al. Among authors: chen l. Gut. 2014 May;63(5):832-43. doi: 10.1136/gutjnl-2012-304037. Epub 2013 Jun 13. Gut. 2014. PMID: 23766440 Free PMC article.

4

Regulatory factors governing adenosine-to-inosine (A-to-I) RNA editing.

Hong H, Lin JS, Chen L. Hong H, et al. Among authors: chen l. Biosci Rep. 2015 Mar 31;35(2):e00182. doi: 10.1042/BSR20140190. Biosci Rep. 2015. PMID: 25662729 Free PMC article. Review.

5

ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer.

Chan TH, Qamra A, Tan KT, Guo J, Yang H, Qi L, Lin JS, Ng VH, Song Y, Hong H, Tay ST, Liu Y, Lee J, Rha SY, Zhu F, So JB, Teh BT, Yeoh KG, Rozen S, Tenen DG, Tan P, Chen L. Chan TH, et al. Among authors: chen l. Gastroenterology. 2016 Oct;151(4):637-650.e10. doi: 10.1053/j.gastro.2016.06.043. Epub 2016 Jul 1. Gastroenterology. 2016. PMID: 27373511 Free PMC article.

6

An RNA editing/dsRNA binding-independent gene regulatory mechanism of ADARs and its clinical implication in cancer.

Qi L, Song Y, Chan THM, Yang H, Lin CH, Tay DJT, Hong H, Tang SJ, Tan KT, Huang XX, Lin JS, Ng VHE, Maury JJP, Tenen DG, Chen L. Qi L, et al. Among authors: chen l. Nucleic Acids Res. 2017 Oct 13;45(18):10436-10451. doi: 10.1093/nar/gkx667. Nucleic Acids Res. 2017. PMID: 28985428 Free PMC article.

7

Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer.

Hong H, An O, Chan THM, Ng VHE, Kwok HS, Lin JS, Qi L, Han J, Tay DJT, Tang SJ, Yang H, Song Y, Bellido Molias F, Tenen DG, Chen L. Hong H, et al. Among authors: chen l. Nucleic Acids Res. 2018 Sep 6;46(15):7953-7969. doi: 10.1093/nar/gky396. Nucleic Acids Res. 2018. PMID: 29796672 Free PMC article.

8

AZIN1 RNA editing confers cancer stemness and enhances oncogenic potential in colorectal cancer.

Shigeyasu K, Okugawa Y, Toden S, Miyoshi J, Toiyama Y, Nagasaka T, Takahashi N, Kusunoki M, Takayama T, Yamada Y, Fujiwara T, Chen L, Goel A. Shigeyasu K, et al. Among authors: chen l. JCI Insight. 2018 Jun 21;3(12):e99976. doi: 10.1172/jci.insight.99976. eCollection 2018 Jun 21. JCI Insight. 2018. PMID: 29925690 Free PMC article.

9

Aberrant hyperediting of the myeloma transcriptome by ADAR1 confers oncogenicity and is a marker of poor prognosis.

Teoh PJ, An O, Chung TH, Chooi JY, Toh SHM, Fan S, Wang W, Koh BTH, Fullwood MJ, Ooi MG, de Mel S, Soekojo CY, Chen L, Ng SB, Yang H, Chng WJ. Teoh PJ, et al. Among authors: chen l. Blood. 2018 Sep 20;132(12):1304-1317. doi: 10.1182/blood-2018-02-832576. Epub 2018 Jul 30. Blood. 2018. PMID: 30061158 Free article.

10

Systematic evaluation and optimization of the experimental steps in RNA G-quadruplex structure sequencing.

Yeung PY, Zhao J, Chow EY, Mou X, Hong H, Chen L, Chan TF, Kwok CK. Yeung PY, et al. Among authors: chen l. Sci Rep. 2019 May 30;9(1):8091. doi: 10.1038/s41598-019-44541-4. Sci Rep. 2019. PMID: 31147619 Free PMC article.

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