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Preclinical Antimalarial Combination Study of M5717, a Plasmodium falciparum Elongation Factor 2 Inhibitor, and Pyronaridine, a Hemozoin Formation Inhibitor.
Rottmann M, Jonat B, Gumpp C, Dhingra SK, Giddins MJ, Yin X, Badolo L, Greco B, Fidock DA, Oeuvray C, Spangenberg T. Rottmann M, et al. Among authors: gumpp c. Antimicrob Agents Chemother. 2020 Mar 24;64(4):e02181-19. doi: 10.1128/AAC.02181-19. Print 2020 Mar 24. Antimicrob Agents Chemother. 2020. PMID: 32041711 Free PMC article.
Parasite Viability as a Measure of In Vivo Drug Activity in Preclinical and Early Clinical Antimalarial Drug Assessment.
Radohery GFR, Walz A, Gumpp C, Cherkaoui-Rbati MH, Gobeau N, Gower J, Davenport MP, Rottmann M, McCarthy JS, Möhrle JJ, Rebelo M, Demarta-Gatsi C, Khoury DS. Radohery GFR, et al. Among authors: gumpp c. Antimicrob Agents Chemother. 2022 Jul 19;66(7):e0011422. doi: 10.1128/aac.00114-22. Epub 2022 Jun 21. Antimicrob Agents Chemother. 2022. PMID: 35727057 Free PMC article.
New In Vitro Interaction-Parasite Reduction Ratio Assay for Early Derisk in Clinical Development of Antimalarial Combinations.
Wicha SG, Walz A, Cherkaoui-Rbati MH, Bundgaard N, Kuritz K, Gumpp C, Gobeau N, Möhrle J, Rottmann M, Demarta-Gatsi C. Wicha SG, et al. Among authors: gumpp c. Antimicrob Agents Chemother. 2022 Nov 15;66(11):e0055622. doi: 10.1128/aac.00556-22. Epub 2022 Oct 5. Antimicrob Agents Chemother. 2022. PMID: 36197116 Free PMC article.
Genetic validation of PfFKBP35 as an antimalarial drug target.
Thommen BT, Dziekan JM, Achcar F, Tjia S, Passecker A, Buczak K, Gumpp C, Schmidt A, Rottmann M, Grüring C, Marti M, Bozdech Z, Brancucci NMB. Thommen BT, et al. Among authors: gumpp c. Elife. 2023 Nov 7;12:RP86975. doi: 10.7554/eLife.86975. Elife. 2023. PMID: 37934560 Free PMC article.