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(Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity.
Humbert N, Kovalenko L, Saladini F, Giannini A, Pires M, Botzanowski T, Cherenok S, Boudier C, Sharma KK, Real E, Zaporozhets OA, Cianférani S, Seguin-Devaux C, Poggialini F, Botta M, Zazzi M, Kalchenko VI, Mori M, Mély Y. Humbert N, et al. Among authors: giannini a. ACS Infect Dis. 2020 Apr 10;6(4):687-702. doi: 10.1021/acsinfecdis.9b00290. Epub 2020 Feb 21. ACS Infect Dis. 2020. PMID: 32045204
Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains.
Mori M, Kovalenko L, Malancona S, Saladini F, De Forni D, Pires M, Humbert N, Real E, Botzanowski T, Cianférani S, Giannini A, Dasso Lang MC, Cugia G, Poddesu B, Lori F, Zazzi M, Harper S, Summa V, Mely Y, Botta M. Mori M, et al. Among authors: giannini a. ACS Chem Biol. 2018 Jan 19;13(1):253-266. doi: 10.1021/acschembio.7b00907. Epub 2017 Dec 28. ACS Chem Biol. 2018. PMID: 29235845
5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein.
Malancona S, Mori M, Fezzardi P, Santoriello M, Basta A, Nibbio M, Kovalenko L, Speziale R, Battista MR, Cellucci A, Gennari N, Monteagudo E, Di Marco A, Giannini A, Sharma R, Pires M, Real E, Zazzi M, Dasso Lang MC, De Forni D, Saladini F, Mely Y, Summa V, Harper S, Botta M. Malancona S, et al. Among authors: giannini a. ACS Med Chem Lett. 2020 Mar 19;11(5):766-772. doi: 10.1021/acsmedchemlett.9b00608. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435383 Free PMC article.
Agreement between an in-house replication competent and a reference replication defective recombinant virus assay for measuring phenotypic resistance to HIV-1 protease, reverse transcriptase, and integrase inhibitors.
Saladini F, Giannini A, Boccuto A, Vicenti I, Zazzi M. Saladini F, et al. Among authors: giannini a. J Clin Lab Anal. 2018 Jan;32(1):e22206. doi: 10.1002/jcla.22206. Epub 2017 Mar 17. J Clin Lab Anal. 2018. PMID: 28303602 Free PMC article.
Synthesis and Evaluation of Bifunctional Aminothiazoles as Antiretrovirals Targeting the HIV-1 Nucleocapsid Protein.
Mori M, Dasso Lang MC, Saladini F, Palombi N, Kovalenko L, De Forni D, Poddesu B, Friggeri L, Giannini A, Malancona S, Summa V, Zazzi M, Mely Y, Botta M. Mori M, et al. Among authors: giannini a. ACS Med Chem Lett. 2018 Dec 7;10(4):463-468. doi: 10.1021/acsmedchemlett.8b00506. eCollection 2019 Apr 11. ACS Med Chem Lett. 2018. PMID: 30996780 Free PMC article.
DDX3X inhibitors, an effective way to overcome HIV-1 resistance targeting host proteins.
Brai A, Riva V, Saladini F, Zamperini C, Trivisani CI, Garbelli A, Pennisi C, Giannini A, Boccuto A, Bugli F, Martini M, Sanguinetti M, Zazzi M, Dreassi E, Botta M, Maga G. Brai A, et al. Among authors: giannini a. Eur J Med Chem. 2020 Aug 15;200:112319. doi: 10.1016/j.ejmech.2020.112319. Epub 2020 May 7. Eur J Med Chem. 2020. PMID: 32446036 Free article.
743 results